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Proteomics in Proximity

Proteomics in Proximity

Proteomics in Proximity discusses the intersection of proteomics with genomics for drug target discovery, the application of proteomics to reveal disease biomarkers, and current trends in using proteomics to unlock biological mechanisms. Co-hosted by Olink's Dale Yuzuki, Cindy Lawley and Sarantis Chlamydas.

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Proteomic Profiling Platforms

The 2022 Science Advances paper, ?Proteomic profiling platforms head to head: Leveraging genetics and clinical traits to compare aptamer- and antibody-based methods? by Daniel H Katz and Rob Gerszten et al. is available online here.

A highly informative Twitter thread by the first author Dr. Daniel Katz reviewing the figures of the paper is available here.

If you are interested in learning more about the use of proteomics in multiomic strategies, here?s link to the Olink website where examples of combinations of omics methods are combined.

If you would like to contact Dale, Cindy or Sarantis feel free to email us at [email protected]

In case you were wondering, Proteomics in Promixity refers to the principle underlying Olink Proteomics assay technology called the Proximity Extension Assay (PEA), and more information about the assay and how it works can be found here.

Would you like to subscribe to the podcast on your favorite player or app? You can do so here: 

Apple Podcasts: https://apple.co/3T0YbSm
Spotify Podcasts: https://open.spotify.com/show/2sZ2wxOqI4b4vSngkajLs8?si=d957d55c8db046f7 Google Podcasts: https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy50cmFuc2lzdG9yLmZtL3Byb3Rlb21pY3MtaW4tcHJveGltaXR5
Amazon Music: https://music.amazon.com/podcasts/d97ace94-f02b-4b37-9532-799548ef2840
Podcast Addict: https://podcastaddict.com/podcast/4098296
Deezer: https://www.deezer.com/show/5178787
Player FM: https://player.fm/series/series-3396598

2022-10-25
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Empower Genomics with Proteomics

Show Notes for PiP Ep 02 ?Empower Genomics with Proteomics?

For more information about the UK Biobank, an Olink to Science blog post called ?Genetic Regulation of the Human Plasma Proteome in the UK Biobank? is available here. The preprint publication itself is available here on bioRxiv

If you?d like to see a great 15 minute presentation on what the goals are for the UK Biobank Pharma Proteomics Project, Dr. Chris Whelan (Biogen) presented this YouTube video at one of the UK Biobank?s scientific meetings that is worth watching.

A paper discussed by Folkersen et al., ?Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals? was published in Nature Metabolism in late 2020, and is available here.

If you would like to contact Dale, Cindy or Sarantis feel free to email us at [email protected] and if you would like to learn more about our backgrounds, Cindy?s LinkedIn is here, Sarantis? is here, and Dale?s is here.

In case you were wondering, Proteomics in Promixity refers to the principle underlying Olink Proteomics assay technology called the Proximity Extension Assay (PEA), and more information about the assay and how it works can be found here.

2022-10-12
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Introduction to Proteomics in Proximity

In case you would like to learn more about our backgrounds, Cindy?s LinkedIn is here, Sarantis? is here, and Dale?s is here.

For more information about the UK Biobank, an Olink to Science blog post called ?Genetic Regulation of the Human Plasma Proteome in the UK Biobank? is available here. The preprint publication itself is available here on bioRxiv. If you?d like to see a great 15 minute presentation on what the goals are for the UK Biobank Pharma Proteomics Project, Dr. Chris Whelan (Biogen) presented this YouTube video at one of the UK Biobank?s scientific meetings that is worth watching.

If you would like to contact Dale, Cindy or Sarantis feel free to email us at [email protected]

In case you were wondering, Proteomics in Promixity refers to the principal underlying Olink Proteomics assay technology called the Proximity Extension Assay (PEA), and more information about the assay and how it works can be found here.

2022-09-27
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The Proteomics in Proximity Podcast Trailer

Co-hosts Dale Yuzuki, Cindy Lawley and Sarantis Chlamydas from Olink Proteomics talk about the intersection of proteomics with genomics for drug target discovery, the application of proteomics to reveal disease biomarkers, and current trends in using proteomics to unlock biological mechanisms.

In case you were wondering, "in Proximity" refers to Olink's underpinning technology called the Proximity Extension Assay, to allow highly multiplexed protein analysis from small sample volumes for pharmaceutical, clinical translation and academic research. More information about PEA can be found here on Olink's website.

If you have any questions or comments, feel free to email us at [email protected]. Thank you for listening!

2022-09-19
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