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The Senatorum Imperialis (officially the Lords Temporal, Martial and Ecclesiarchical of the Most Divine and Righteous Imperium of Mankind) collectively form the Council of the High Lords of Terra. The Senatorum is an Imperial governing body led by twelve leaders of the most powerful organisations of the Imperium. This body rules the Imperium in the Emperor's name. The Senatorum itself is composed of tens of thousands of Imperial dignitaries, nobleman, lords, and other officials, but these rarely meet and instead the "High Twelve" conduct the vast majority of affairs.
The task of the High Lords is to interpret and enact the will of the Emperor. Accordingly, the position of High Lord was the most powerful in the Imperium until the reemergence of Roboute Guilliman, who declared himself Imperial Regent, or the Emperor's Living Voice.