152 - Vascular Contributions to Alzheimer's Disease & Treatments targeting the Vasculature: March 2021

Tired of the age-old amyloid cascade hypothesis? So is Elyn! Join her in this episode unpacking papers that showed up on PubMed in March 2021 that add more evidence to the tight intertwinement of vascular and brain health. Topics in this episode range from mechanistic studies in animal models looking at cerebral blood flow and blood-brain barrier integrity, all the way to clinical studies mapping out cerebrovascular damage across the AD continuum. This is a shorter episode, with only 13 papers covered - perfect for a commute to work or a leisurely bike ride!  

Sections in this episode:  

Overlap Between Cardiovascular Disease and AD (3:48)  

Clinical Studies on Cerebrovascular Pathology (12:03)  

Mechanisms of Blood-Brain Barrier Disruption (18:00)  

AD Treatments Targeting the Vasculature (21:14)  

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You can find the bibliography for this episode by clicking here. 

To access the folder with all the bibliographies for 2021 so far, follow this link (it will be updated as we publish episodes and process bibliographies), or click the following link below:

https://drive.google.com/drive/folders/1N1zx_itPkCDNYE1yFGZzQxDDR-NiRx3p?usp=sharing

You can also join our mailing list to receive a newsletter once per month by filling this form. 

Or tweet at us: @AMiNDR_podcast  

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Please help us by spreading the word about AMiNDR to your friends, colleagues, and networks! Another way you can help us reach more researchers is by leaving us a review on Apple Podcasts. 

We would like to thank our amazing team for all of the work that goes into every episode of AMiNDR. Today's episode was scripted and hosted by Elyn Rowe, reviewed by Courtney Kloske and edited by Michelle Grover. The bibliography was created by Jacques Ferreira and the wordcloud was generated by Sarah Louadi (www.wordart.com). Big thanks to the sorting team for sorting all the papers published in March into themes for our episodes, and to our management team, which includes Sarah Louadi, Ellen Koch, Naila Kuhlmann, Elyn Rowe, Anusha Kamesh, and Jacques Ferreira, for keeping everything running smoothly.

Our music is from "Journey of a Neurotransmitter" by musician and fellow neuroscientist Anusha Kamesh; you can find the original piece and her other music on soundcloud under Anusha Kamesh or on her YouTube channel, AKMusic.   

https://www.youtube.com/channel/UCMH7chrAdtCUZuGia16FR4w   

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Elyn Rowe would like to acknowledge her support from the Alzheimer Society of Canada, through the Alzheimer Society Research Program. The Alzheimer Society is committed to knowledge dissemination as a key pillar in their mission to  promote the search for causes, treatments, and a cure for Alzheimer disease.

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If you are interested in joining the team, send us your CV by email. We are specifically looking for help with sorting abstracts by topic, abstract summaries and hosting, creating bibliographies, and promotions. However, if you are interested in helping in other ways, don't hesitate to apply anyways.  

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*About AMiNDR: *  

Learn more about this project and the team behind it by listening to our first episode: "Welcome to AMiNDR!"