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AMiNDR: A Month in Neurodegenerative Disease Research

163 - Treatments targeting Oxidative Stress & Metabolism in Alzheimer's disease: March 2021

44 min • 29 maj 2021

If you are interested in oxidative stress in Alzheimer’s disease, mitochondrial dysfunction, or metabolism, come hear about the ways they can be targeted for therapeutic purposes. Maybe you are tired of hearing about cholinesterase inhibitors or anti-amyloid-beta antibodies and want to explore something different. Tune in with Sarah in this last episode for our series on the papers published in March 2021. She covers 17 abstracts that harness the interconnectedness between mechanisms involved in AD pathology to develop new therapeutics and repurpose others (used in diabetes, hypertension, depression,…)  

Ready. Set. Play!
 

Sections in this episode:

Targeting oxidative stress (4:00)

Targeting mitochondria (14:40)

Targeting metabolism (with a focus on diabetes and insulin) (21:47)

Targeting metabolism (with a focus on cholesterol) (30:48)

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To access the folder with all the bibliographies for 2021 so far, follow this link (it will be updated as we publish episodes and process bibliographies), or click the following link below:

https://drive.google.com/drive/folders/1N1zx_itPkCDNYE1yFGZzQxDDR-NiRx3p?usp=sharing

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Please help us by spreading the word about AMiNDR to your friends, colleagues, and networks! Another way you can help us reach more researchers is by leaving us a review on Apple Podcasts. 

We would like to thank our amazing team for all of the work that goes into every episode of AMiNDR. Today's episode was scripted by Marcia Jude, the reviewed, hosted  and edited by Sarah Louadi. The bibliography was created by Satish Kumar and the wordcloud was generated by Sarah Louadi (www.wordart.com). Big thanks to the sorting team for sorting all the papers published in March into themes for our episodes, and to our management team, which includes Sarah Louadi, Ellen Koch, Naila Kuhlmann, Elyn Rowe, Anusha Kamesh, and Jacques Ferreira, for keeping everything running smoothly.

Our music is from "Journey of a Neurotransmitter" by musician and fellow neuroscientist Anusha Kamesh; you can find the original piece and her other music on soundcloud under Anusha Kamesh or on her YouTube channel, AKMusic.   

https://www.youtube.com/channel/UCMH7chrAdtCUZuGia16FR4w   

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*About AMiNDR: *  

Learn more about this project and the team behind it by listening to our first episode: "Welcome to AMiNDR!" 

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