189 - Vascular Contributions to Alzheimer's Disease & Treatments Targeting the Vasculature: June 2021

With a shorter epsiode than usual this month, Elyn is back with an update on vascular contributions to Alzheimer disease and potential treatment avenues targeting the vasculature. Tune in for a summary of 8 papers spanning clinical studies that unpack neuroimaging hallmarks of vascular changes in AD, all the way to mechanistic studies focused on understanding blood-brain barrier dysfunction in Alzheimer disease, and a bonus inclusion of a fluid biomarkers paper on the plasma lipidome!  

Sections in this episode:  

Clinical Studies – Neuroimaging and Cardiovascular Risk (4:20)  

Mechanistic Studies – BBB dysfunction and rescue (13:20)  

Bonus paper on Plasma lipidome (17:38) 

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To access the folder with all the bibliographies for 2021 so far, follow this link (it will be updated as we publish episodes and process bibliographies), or click the following link below:

https://drive.google.com/drive/folders/1N1zx_itPkCDNYE1yFGZzQxDDR-NiRx3p?usp=sharing

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Or tweet at us: @AMiNDR_podcast  

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Please help us by spreading the word about AMiNDR to your friends, colleagues, and networks! Another way you can help us reach more researchers is by leaving us a review on Apple Podcasts or wherever you listen to podcasts. 

We would like to thank our amazing team for all of the work that goes into every episode of AMiNDR. Today's episode was scripted and hosted by Elyn Rowe, edited by Michelle Grover, and reviewed by Jacques Ferreira and Anusha Kamesh. The bibliography was created by Tarini Boparai and the wordcloud (wordart.com) was generated by Sarah Louadi. 

Big thanks to the sorting team for sorting all the papers published in June into themes for our episodes: Jacques Ferreira, Elyn Rowe, Ellen Koch, Christy Yu, Nicole Corso, Sarah Louadi, and Naila Kuhlmann. 

Also, props to our management team, which includes Sarah Louadi, Ellen Koch, Naila Kuhlmann, Elyn Rowe, Anusha Kamesh, and Jacques Ferreira, for keeping everything running smoothly.

Our music is from "Journey of a Neurotransmitter" by musician and fellow neuroscientist Anusha Kamesh; you can find the original piece and her other music on soundcloud under Anusha Kamesh or on her YouTube channel, AKMusic.   

https://www.youtube.com/channel/UCMH7chrAdtCUZuGia16FR4w   

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Elyn Rowe would like to acknowledge her support from the Alzheimer Society of Canada, through the Alzheimer Society Research Program. The Alzheimer Society is committed to knowledge dissemination as a key pillar in their mission to  promote the search for causes, treatments, and a cure for Alzheimer disease.

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If you are interested in joining the team, send us your CV by email. We are specifically looking for help with sorting abstracts by topic, abstract summaries and hosting, creating bibliographies, and promotions. However, if you are interested in helping in other ways, don't hesitate to apply anyways.  

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*About AMiNDR: *  

Learn more about this project and the team behind it by listening to our first episode: "Welcome to AMiNDR!"