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AMiNDR: A Month in Neurodegenerative Disease Research

227 - Autophagy & Proteostasis in Alzheimer's Disease: September 2021

33 min • 23 november 2021

Tune into this month's episode on the latest research on autophagy and proteostasis in Alzheimer's Disease. This includes papers on how autophagy and protein homeostasis are dysfunctional in this disease, and potential treatments that target these cellular pathways. Enjoy!  

Sections in this episode:  

Proteostatic and autophagic dysregulation (4:33)  

RNA splicing, binding, and signaling (10:32)  

Glycans, glycoproteins, and fatty acids (19:29)  

Amyloid precursor protein (24:16)  

Targeting Proteostasis/Autophagy Machinery (26:55) 

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You can find the numbered bibliography for this episode by clicking here, or the link below:

https://drive.google.com/file/d/1F8xBFPGIJ5sVNGy_-Mb6PCeWpxJ7YNqh/view?usp=sharing

To access the folder with all the bibliographies for 2021 so far, follow this link (it will be updated as we publish episodes and process bibliographies), or click the following link below:

https://drive.google.com/drive/folders/1N1zx_itPkCDNYE1yFGZzQxDDR-NiRx3p?usp=sharing

You can also join our mailing list to receive a newsletter by filling this form. 

Or tweet at us: @AMiNDR_podcast  

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Please help us by spreading the word about AMiNDR to your friends, colleagues, and networks! Another way you can help us reach more listeners who would benefit from the show is by leaving us a review on Apple Podcasts or wherever you listen to podcasts. It helps us a lot and we thank you in advance for leaving a review! 

Our team of volunteers works tirelessly each month to bring you every episode of AMiNDR. This episode was scripted and hosted by Kate Van Pelt, edited by Michelle Grover, and reviewed by Naila Kuhlmann and Anusha Kamesh. The bibliography was made by Lara Onbasi and the wordcloud by Sarah Louadi (www.wordart.com). 

Big thanks to the sorting team for taking on the enormous task of sorting all of the Alzheimer’s Disease papers into episodes each month. For September 2021, the sorters were Jacques Ferreira, Ellen Koch, Christy Yu, Sarah Louadi, Kate Van Pelt, Nicole Corso, Eden Dubchak, Kira Tosefsky, Dana Clausen, and Elyn Rowe.

Also, props to our management team, which includes Sarah Louadi, Ellen Koch, Naila Kuhlmann, Elyn Rowe, Anusha Kamesh, Jacques Ferreira, and Shruti Kocchar for keeping everything running smoothly.

Our music is from "Journey of a Neurotransmitter" by musician and fellow neuroscientist Anusha Kamesh; you can find the original piece and her other music on soundcloud under Anusha Kamesh or on her YouTube channel, AKMusic.   

https://www.youtube.com/channel/UCMH7chrAdtCUZuGia16FR4w   

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If you are interested in joining the team, send us your CV by email. We are specifically looking for help with sorting abstracts by topic, abstract summaries and hosting, audio editing, creating bibliographies, and outreach/marketing. However, if you are interested in helping in other ways, don't hesitate to apply anyways.  

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*About AMiNDR: *  

Learn more about this project and the team behind it by listening to our first episode: "Welcome to AMiNDR!" 

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