Preclinical Testing - Part 3: Alzheimer's Disease June 2020

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!

In this episode, Marcia covers papers published in June 2020 on treatment development done on animal models, targeting metabolism, mitochondria, oxidative stress, the gut microbiome, inflammatory pathways, glia, and autophagy. If you are interested in learning more about these pathological events, you should check out our episode on these disease mechanisms, covered by Anusha. We also have a number of episodes dedicated to pre-clinical testing, split by the intended target the cholinergic system, the glutamatergic system, synaptic function, tau, amyloid-beta, cognitive performance, and other multitargeted approaches.  

Enjoy!

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List of sections in this episode: 

(0.57)   Metabolism / lipids

(3.40)   The gut microbiome

(5.00)   Autophagy

(8.10)     Mitochondria

(10.54)   Oxidative stress

(18.25)   Inflammatory pathways/ glia

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Today's episode was scripted and hosted by Marcia Jude, edited by Anusha Kamesh, and made possible by an entire team of volunteers behind the scenes.  

Our music is from "Journey of a Neurotransmitter" by musician and fellow neuroscientist Anusha Kamesh; you can find the original piece and her other music on soundcloud under Anusha Kamesh or on her YouTube channel, AKMusic 

https://www.youtube.com/channel/UCMH7chrAdtCUZuGia16FR4w 

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*About AMiNDR: *

Learn more about this project and the team behind it by listening to our first episode: "Welcome to AMiNDR!"