DNA Methylation, Lateral Ventricular Volume, and Psychiatric Risk for Schizophrenia

26 min • 18 december 2023

DOI: 10.13056/acamh.25592

In this Papers Podcast, Dr. Charlotte Cecil and Dr. Mannan Luo discuss their co-authored JCPP paper ‘DNA methylation at birth and lateral ventricular volume in childhood: a neuroimaging epigenetics study’ (https://doi.org/10.1111/jcpp.13866).

There is an overview of the paper, methodology, key findings, and implications for practice.

Discussion points include:

Definitions of ‘lateral ventricular volume enlargement’ and ‘epigenetics process of DNA methylation’.
The advantage of capturing DNA methylation at different life stages.
How this approach will further knowledge in this field.
Implications of the findings for researchers, and clinicians.
Potential follow-up studies.

In this series, we speak to authors of papers published in one of ACAMH’s three journals. These are The Journal of Child Psychology and Psychiatry (JCPP); The Child and Adolescent Mental Health (CAMH) journal; and JCPP Advances.

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