The human body is tempered by cellular fate paradigms that include senescence vs. proliferation during aging. A corruption in the senescnce associated secretory phenotype may be a proximal tareget to reduce aging morbidity but does it not open the door to oncogenesis and the potential for autoimmune disease?
Comput Struct Biotechnol J. 2019; 17: 1151–1161
Nat Med. 2017 Jun; 23(6): 775–781
Support your biochemistry podcast! Be "Authentic" and send donations now!
Dr Guerra thanks you !