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Behind the Breakthroughs

Zip Codes, Smart Glasses, and DNA: The Future of Precision Public Health

40 min • 19 mars 2025

Josh Denny, MD, is a trailblazer in precision medicine whose journey was deeply influenced by his family’s struggles with cystic fibrosis, a disease that claimed the lives of four of his grandparents’ children. This personal connection fueled his pursuit of a career blending medicine, genetics, and technology, leading to groundbreaking work in medical informatics and personalized healthcare.


In this episode of Behind the Breakthroughs, we delve into Josh’s leadership of the All of Us Research Program. Since its launch in 2018, this ambitious initiative has enrolled 850,000 participants and collected over 400,000 genomic profiles. Its goal: to harness diverse biological data to advance understanding of health disparities, rare diseases, and common conditions. Discover how Josh’s work is revolutionizing healthcare, from life-saving genetic testing to targeted therapies, and shaping a future where medicine is tailored to every individual’s unique genetic and environmental profile.


Stay up to date with the latest episodes of Behind the Breakthroughs by subscribing to the IPM eNewsletter here.


Produced by Bill Levine

Hosted by Jonathan D. Grinstein

Music provided by Artem Hramushkin

Audio mixed and mastered by Jason Mack


Hosted on Acast. See acast.com/privacy for more information.

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