Sunday, May 16, 2021: President Biden marks a critical milestone in the fight against Covid

The CDC has a new message for vaccinated Americans: it's safe to lose the mask, whether you're indoors or outside. But many health experts worry it may be too soon.

Plus, a crisis in the Mideast and gas shortages along the eastern seaboard threaten to distract the White House from President Biden's top priorities.

And ousted GOP leader Rep. Liz Cheney vows to take on Trump's election fraud claims, even as members of her own party continue to propagate those lies.

On today's show: CNN's Manu Raju; Jackie Kucinich of the Daily Beast; Michael Shear of the New York Times;  POLITICO’s Melanie Zanona; and CNN Medical Analyst Dr. Leana Wen.

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