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DMPK Insights

DMPK Insights #5: Mass Spectrometry Imaging - Past, Present and Future

31 min • 21 september 2023

In this podcast, Josephine Bunch, Principal Research Scientist and Co-Director of the National Centre of Excellence in Mass Spectrometry (NiCE-MSI) at NPL,  talks about her work, and in particular her involvement in the Cancer Research UK Grand Challenge Programme.  

The episode explores the following:

  • Recent innovations in MSI 
  • Challenges associated with analyzing ever more complex molecules
  • Label-free vs labelled imaging
  • Hardware and software improvements and how these affect the industry
  • Combining imaging techniques to extract maximum information
  • Exciting developments for the future, including personalized medicine and the innovative technologies that will make this a reality

Speaker:
Josephine Bunch, Ph.D. -
Principal Research Scientist and Co-Director of the National Centre of Excellence in Mass Spectrometry Imaging (NiCE-MSI) at NPL

Josephine completed a Ph.D. in mass spectrometry imaging at Sheffield Hallam University, followed by a post-doc appointment at the University of Sheffield. Josephine then led a research group at the University of Birmingham, where she also lectured in Chemistry and Imaging. Josephine is currently based at the National Physics Laboratory where she is Co-Director of the National Centre of Excellence in Mass Spectrometry Imaging (NiCE-MSI) and is also Chair of Biomolecular Mass Spectrometry at Imperial College London.  She is currently leading the Cancer Research UK Grand Challenge programme – a fascinating project that aims to deliver new insights into cancer and cancer treatments using the latest mass spectrometry imaging techniques. 


Stay tuned for more podcasts in our Pharmaron DMPK Insights Series!

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