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Do You F*cking Mind?

295. The Neuroscience of Antidepressants Pt 1. Drugs based around the monoamine hypothesis

25 min • 28 januari 2024

There’s a lot of talk about the monoamine hypothesis of Depression, which is the theory that a reduced level of serotonin, dopamine and norepinephrine in the central nervous system is what causes symptoms of depression, but is it the cause?

In this episode we’ll find out what the evidence is, and what treatments work based on that hypothesis, and how they relate to the drugs that are currently on the market to treat symptoms of Depression. In the next episode we'll go into more detail about the glutamatergic system and how these drugs interact with the brain, and potentially new treatments that could potentially reverse the negative side effects of some of the existing treatments.

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CREDITS

Host: Alexis Fernandez       
Executive Producer & Editor: Elise Cooper
Digital Producer: Zoe Panaretos
DYFM Social Producer: Shania Magua
Managing Producer: Sam Cavanagh 

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