What starts off as a generous act from the new proprietor of the Feed and Seed soon turns into Pestilence on the prairie. With the residents of Walnut Grove now stuck at home under quarantine and the school turned into a makeshift hospital, Doc Baker with the help of Charles and Reverend Alden tend to the patients. But, when will it all end? What is the source? Will they run out of Ice? And why is the wind blowing so much? Walnut Grove is fighting its own pandemic.