Dr. Karl Deisseroth, MD, PhD, is a clinical psychiatrist and scientist who directs a bioengineering research laboratory at Stanford University School of Medicine. His work aims to understand and develop treatments for disorders of the mind such as depression, attention deficit disorders (ADHD & ADD), autism, schizophrenia, anxiety, eating disorders, borderline personality and obsessive-compulsive disorder. We discuss his experience treating his patients and his laboratory’s mission to find and develop cures for mental disease and tools for probing how the brain works.
Read the full show notes for this episode at hubermanlab.com.
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00:00:00 Introduction
00:03:47 Sponsors: AG1, LMNT & Waking Up
00:07:41 Using Language to Understand the Mind
00:12:19 Blood Tests For Mental Disease
00:13:38 The Largest Challenges Facing Treatment of Mental Health
00:20:21 Predicting Depression & Suicide
00:22:47 Drugs That Work for Brain Illness
00:27:01 What Would A Cure For the Broken Mind Look Like?
00:32:23 Channelopsins: Tools For Understanding & Treating the Mind
00:39:10 Curing Blindness with Channelopsins
00:41:58 Why Karl Became a Scientist
00:47:10 Vagus Nerve In Depression
00:54:12 Challenges To Overcome for Treating Mental Illness with Channelopsins
00:58:34 Using the Dialogue with Patients to Guide Treatment
01:00:52 How Our Eyes Reveal Our Mental Health
01:06:04 Controlling Structures Deep In the Brain
01:08:23 The Most Effective Drugs Often Have the Most Side Effects
01:09:50 Do Psychiatrists Take the Drugs They Prescribe
01:14:15 Moving From Experimental Tools To Novel Treatments
01:16:00 Brain-Machine Interfaces & Neuralink
01:19:30 ADHD & Dr. Deisseroth’s Approach To Focusing His Mind
01:26:36 How Dr. Deisseroth Balances A Career In Medicine, Science & Family
01:35:41 New Ways of Exploring Brains: CLARITY
01:38:49 What Is Special About the Human Brain?
01:46:03 Psychedelics
01:54:12 MDMA
01:57:15 Dr. Deisseroth’s New Book “Projections: A Story of Emotions”
01:59:42 Connecting with Dr. Deisseroth on Twitter