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Discovering the Microbiome with Leo Grady from Jona

23 min • 22 april 2024

What if AI could decode the mysteries of your microbiome for a healthier you? In this episode, I sit down with Leo Grady, Founder and CEO of Jona, to discuss his groundbreaking work in microbiome research. Jona is a health technology company that specializes in microbiome profiling and analysis. It offers microbiome testing kits for individuals to use at home, along with AI-powered analysis of the associated microbiome data. In our conversation, we delve into the human microbiome and how Jona is harnessing the power of AI to unlock its secrets and revolutionize healthcare practices. Discover how Jona bridges the gap between research and clinical practice and utilizes deep shotgun metagenomic sequencing. We discuss why he thinks AI is a critical technology for decoding the microbiome, how Jona is able to connect research findings to microbiome profiles, and the company’s approach to model validation. Gain insights into the evolving landscape of AI in healthcare, the number one barrier to clinical translation and adoption of AI technology, what needs to be done to overcome it, and much more.


Key Points:

  • Background about Leo and what motivated him to start Jona.
  • He explains the complexity of the microbiome and its role in human health.
  • Hear more about Jona and how the company leverages AI for data analysis.
  • How Jona applies models to analyze microbiome data and medical literature.
  • The technical nuances and validation processes behind the company’s approach.
  • Learn about the challenges of building models to elucidate microbiome data.
  • Explore the intricacies of validating the company’s groundbreaking technology.
  • Advancements in AI and machine learning that he is most excited about.
  • Leo shares advice for leaders of AI-powered startups.
  • Uncover the number one barrier to AI adoption: payment. 
  • What the future looks like for Jona and what the company aims to achieve.


Quotes:

“What's really remarkable to me about the microbiome is that it's been linked to almost every aspect of human health.” — Leo Grady

“There are a lot of challenges that forced us to really develop new kinds of [machine learning] techniques that are really suited to this problem. We can't just rely on taking what's out there today.” — Leo Grady


“The AI is doing that extraction. We have human oversight to make corrections to it. But once that paper has been extracted correctly, then we don't need to look at it again. It’s a one-time review process on every study.” — Leo Grady


“I think the biggest challenges with AI and healthcare today are no longer technical, and they're no longer regulatory. The fact is that with current AI technology and enough data, we can solve almost any AI problem that we want to.” — Leo Grady


Links:

Leo Grady on LinkedIn

Jona


Resources for Computer Vision Teams:

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