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Impact AI

Virtual Tissue Staining with Yair Rivenson from PictorLabs

34 min • 6 maj 2024

Welcome to today’s episode of Impact AI, where we dive into the groundbreaking world of virtual tissue staining with Yair Rivenson, the co-founder and CEO of PictorLabs, a digital pathology company advancing AI-powered virtual staining technology to revolutionize histopathology and accelerate clinical research to improve patient outcomes. You’ll find out how machine learning is used to translate unstained tissue autofluorescence into diagnostic-ready images, gain insight into overcoming AI hallucinations and the rigorous validation processes behind virtual staining models, and discover how PictorLabs navigates challenges like large files and bandwidth dependency while seamlessly integrating technology into clinical workflows. Yair also provides invaluable advice for AI-powered startup leaders, emphasizing the importance of automation and data quality. To gain deeper insights into the transformative potential of virtual tissue staining, tune in today!


Key Points:

  • The origin story of PictorLabs and the research that informed it.
  • Why Pictor’s work is so important for patients and the healthcare system.
  • What Yair means when he says machine learning is the “engine” for virtual staining.
  • How Pictor mitigates the challenge of AI hallucinations.
  • Insight into what goes into validating virtual staining models.
  • Large files, bandwidth dependency, and other challenges that Pictor faces.
  • A look at how this technology fits smoothly into the clinical workflow.
  • Collaborating with economic partners while staying focused on business objectives.
  • Yair’s product-focused advice for leaders of AI-powered startups
  • What the next three to five years looks like for PictorLabs.


Quotes:


“The most important factor for the healthcare system, for the patient is the fact that you can get all the results, all the workup, and all the different stains from a single tissue section very, very fast.” — Yair Rivenson


“Machine learning is the engine behind virtual staining. In a sense, that’s what takes those images from the autofluorescence of the unstained tissue section and converts [them] into a stain that pathologists can use for their diagnostics.” — Yair Rivenson


“At the end of the day, the network is as good as the data that it learns from.” — Yair Rivenson


“The more you automate, the better off you’ll be in the long run.” — Yair Rivenson


Links:

Yair Rivenson

PictorLabs

PictorLabs on LinkedIn

‘Virtual histological staining of unlabelled tissue-autofluorescence images via deep learning’

‘Assessment of AI Computational H&E Staining Versus Chemical H&E Staining For Primary Diagnosis in Lymphomas’


Resources for Computer Vision Teams:

LinkedIn – Connect with Heather.

Computer Vision Insights Newsletter – A biweekly newsletter to help bring the latest machine learning and computer vision research to applications in people and planetary health.

Computer Vision Strategy Session – Not sure how to advance your computer vision project? Get unstuck with a clear set of next steps. Schedule a 1 hour strategy session now to advance your project.

Foundation Model Assessment – Foundation models are popping up everywhere – do you need one for your proprietary image dataset? Get a clear perspective on whether you can benefit from a domain-specific foundation model.

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