In Episode 1 we're talking about Kuru, AKA "The Laughing Death", the first infectious spongiform encephalopathy (I dare you to say that 10 times fast) to be discovered and described among humans. We'll dive straight into the heart of the Kuru epidemic in Papua New Guinea, describe its mysterious and intriguing origins, and tell you everything you need to know about what a prion is and how they work!