Graham Mooney (Johns Hopkins University) talks to Merle and Lee about the key roles of place and space in how we understand disease in the modern world. After defining these terms and offering a few examples of how to research them, Graham discusses the key role of disease surveillance and tof state coercion in imperial centers and their colonies. He then turns to talk about changes in public health in the last half century, with a focus on the city of Baltimore. At the end, Graham reflects on all of these ideas in light of the Covid pandemic.