The New Penicillin? Pharmacotherapy for Obesity

Join Drs Nihar Desai and Neda Rasouli as they discuss the evolution of obesity treatment over the past two decades, including the latest novel therapies.

Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/999845. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Cardiovascular-Kidney-Metabolic (CKM) Syndrome: A State-of-the-Art Review https://pubmed.ncbi.nlm.nih.gov/38103820/

Obesity https://emedicine.medscape.com/article/123702-overview

A Synopsis of the Evidence for the Science and Clinical Management of Cardiovascular-Kidney-Metabolic (CKM) Syndrome: A Scientific Statement From the American Heart Association https://pubmed.ncbi.nlm.nih.gov/37807920/

Obesity and Severe Obesity Prevalence in Adults: United States, August 2021–August 2023 https://www.cdc.gov/nchs/products/databriefs/db508.htm

Physiology, Obesity Neurohormonal Appetite and Satiety Control https://www.ncbi.nlm.nih.gov/books/NBK555906/

Melanocortin-4 Receptor Complexity in Energy Homeostasis, Obesity and Drug Development Strategies https://pubmed.ncbi.nlm.nih.gov/34882941/

Bariatric Surgery https://emedicine.medscape.com/article/197081-overview

The Effects of Bariatric Surgery on Cardiovascular Outcomes and Cardiovascular Mortality: A Systematic Review and Meta-Analysis https://pubmed.ncbi.nlm.nih.gov/36909063/

Semaglutide and Cardiovascular Outcomes in Obesity Without Diabetes https://pubmed.ncbi.nlm.nih.gov/37952131/

Comparison of Tirzepatide and Dulaglutide on Major Adverse Cardiovascular Events in Participants With Type 2 Diabetes and Atherosclerotic Cardiovascular Disease: SURPASS-CVOT Design and Baseline Characteristics https://pubmed.ncbi.nlm.nih.gov/37758044/

A Study of Tirzepatide (LY3298176) on the Reduction on Morbidity and Mortality in Adults With Obesity (SURMOUNT-MMO) https://clinicaltrials.gov/study/NCT05556512

Effects of Semaglutide on Chronic Kidney Disease in Patients With Type 2 Diabetes https://pubmed.ncbi.nlm.nih.gov/38785209/