A. Espay and B. Stecher, "Brain Fables: The Hidden History of Neurodegenerative Diseases and a Blueprint to Conquer Them" (Cambridge UP, 2020)

An estimated 80 million people live with a neurodegenerative disease, with this number expected to double by 2050. Despite decades of research and billions in funding, there are no medications that can slow, much less stop, the progress of these diseases. The time to rethink degenerative brain disorders has come. With no biological boundaries between neurodegenerative diseases, illnesses such as Parkinson's and Alzheimer's result from a large spectrum of biological abnormalities, hampering effective treatment. In Brain Fables: The Hidden History of Neurodegenerative Diseases and a Blueprint to Conquer Them (Cambridge UP, 2020), acclaimed neurologist Dr Alberto Espay and Parkinson's advocate Benjamin Stecher present compelling evidence that these diseases should be targeted according to genetic and molecular signatures rather than clinical diagnoses. There is no Parkinson's or Alzheimer's, simply people with Parkinson's or Alzheimer's. An incredibly important story never before told, Brain Fables is a wakeup call to the scientific community and society, explaining why we have no effective disease-modifying treatments, and how we can get back on track.

Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. You can reach her at [email protected].

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