Episode 19 of the Performance Around the Clock podcast comes from the 2024 Society for Research on Biological Rhythms (SRBR) biennial meeting in San Juan, Puerto Rico. We have the honor to talk with one of the pillars of the circadian field - Dr. Joseph Takahashi. Dr. Takahashi pioneered the use of forward genetics and positional cloning in mouse as a tool to discover genes that underlie neurobiology and behavior. His discovery of clock genes led to a description of a conserved circadian clock mechanism in animals. In this podcast, we hear about how his lab discovered and cloned the mouse circadianClock gene. In addition, we find out how circadian alignment of feeding, daily fasting and caloric restriction can combine to increase longevity.
Dr. Takahashi has authored more than 300+ scientific publications and the recipient of many awards and distinctions including:
The Honma Prize in Biological Rhythms Research
NSF Presidential Young Investigator Award
Searle Scholars Award
Bristol-Myers Squibb Unrestricted Grant in Neuroscience, and the C. U. Ariens Kappers Medal. W. Alden Spencer Award in Neuroscience from Columbia University
Fellow of the American Academy of Arts and Sciences
Member of the National Academy of Sciences
Member of the National Academy of Medicine
Gruber Neuroscience Prize at the Society for Neuroscience
Guest:
Dr. Joseph Takahashi
Chair of the Department of Neuroscience at UT Southwestern Medical Center
Loyd B. Sands Distinguished Chair in Neuroscience
X (formerly Twitter): @CircadianClocks
https://twitter.com/circadianclocks
UT Southwestern profile:
https://profiles.utsouthwestern.edu/profile/105885/joseph-takahashi.html
Lab webpage:
https://labs.utsouthwestern.edu/takahashi-lab
Host:
Dr. Satchin Panda
@SatchinPanda
https://x.com/SatchinPanda
Instagram: @satchin.panda
https://www.instagram.com/satchin.panda/
Links:
Donations: https://panda.salk.edu/giving/
Research: https://www.salk.edu/scientist/satchidananda-panda/
More science: https://mycircadianclock.org/