The shortage of organs donated for transplantation is resulting in the deaths of three people daily in addition to being burdensome on the NHS, which has to provide costly treatments. Quantitative surveys on the attitudes of British Muslims towards donation reveal that although the majority say that they are happy to receive an organ if needed, they are reluctant to become donors. Individuals feel constrained by advice from religious leaders and the interpretation of religious scriptures, considering organ donation to contravene Sharia rulings. In light of the imminent transition towards a system of ‘deemed consent’, in which there is a presumption that everyone is willing to donate their organs, Muslims are faced with the question of whether they want to opt out of saving, potentially, several lives.