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the bioinformatics chat

#6 Allele-specific expression

33 min • 25 juni 2017

I talk about allele-specific expression: why it arises and how it can be reliably detected.

Sections:

  • The biology of allele-specific expression (2:17)
  • Detecting allele-specific expression with RNA-seq (7:46)
  • Mapping and sequencing biases (16:39)
  • The experiment in yeast (19:47)
  • Statistical models (21:44)

Links:

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