Drs Harrington and Gibson provide their annual roundup of what they consider the key cardiovascular trials of 2021. This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit
This podcast is intended for US healthcare professionals only.
To read a full transcript of this episode or to comment please visit:
https://www.medscape.com/viewarticle/963475
https://www.medscape.com/author/bob-harrington
Antiplatelet Therapy
Comparative Effectiveness of Aspirin Dosing in Cardiovascular Disease
https://doi.org/10.1056/NEJMoa2102137
Dual Antiplatelet Therapy after PCI in Patients at High Bleeding Risk
https://doi.org/10.1056/NEJMoa2108749
Effect of 1-Month Dual Antiplatelet Therapy Followed by Clopidogrel vs 12-Month Dual Antiplatelet Therapy on Cardiovascular and Bleeding Events in Patients Receiving PCI
https://doi.org/10.1001/jama.2019.8145
Aspirin Versus Clopidogrel for Chronic Maintenance Monotherapy After Percutaneous Coronary Intervention (HOST-EXAM): An Investigator-Initiated, Prospective, Randomised, Open-Label, Multicentre Trial
https://doi.org/10.1016/S0140-6736(21)01063-1
SGLT2 Inhibitors and GLP-1 Agonists
Empagliflozin in Heart Failure with a Preserved Ejection Fraction
https://www.nejm.org/doi/full/10.1056/NEJMoa2107038
Once-Weekly Semaglutide in Adults with Overweight or Obesity
https://www.nejm.org/doi/full/10.1056/NEJMoa2032183
Cardiac Surgery and PCI
Left Atrial Appendage Occlusion during Cardiac Surgery to Prevent Stroke
https://doi.org/10.1056/NEJMoa2101897
Concomitant Tricuspid Repair in Patients with Degenerative Mitral Regurgitation
https://doi.org/10.1056/NEJMoa2115961
Fractional Flow Reserve–Guided PCI as Compared with Coronary Bypass Surgery
https://doi.org/10.1056/NEJMoa2112299
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