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The Curbsiders Internal Medicine Podcast

#479 Managing Treatment-Resistant Depression featuring Dr. Jessi Gold

94 min • 14 april 2025
Lead the way in depression management! We’re joined by Dr. Jessi Gold, a psychiatrist and mental health advocate, who provides essential pearls on ways to recognize the multifaceted nature of depression and similarly presenting medical conditions. We also discuss the complexities of treatment options including various medication options and therapies, and how to choose between these treatments.

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Show Segments

  • Intro
  • Case 1 from Kashlak
  • Medical conditions that can mimic depression
  • Diagnosis of depression
  • How to explain depression to family
  • Initial treatment options for depression
  • Case 2 from Kashlak
  • Suicide risk assessment
  • Trialing, augmenting, and tapering of medications
  • Pharmacogenetic testing
  • Alternate treatment options: TMS, ECT, ketamine, psilocybin, cannabis
  • Outro

Credits

  • Written and Produced by: Zoya Surani
  • Show Notes, Infographic, and Cover Art: Zoya Surani
  • Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP   
  • Reviewer: Sai Achi MD,MBA,FACP
  • Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
  • Technical Production: PodPaste
  • Guest: Jessi Gold, MD

Disclosures

Dr. Gold reports no relevant financial disclosures. The Curbsiders report no relevant financial disclosures. 


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