From Diabetes to Dementia: A Gut Microbiome Exploration With Dr Hariom Yadav

Hello and Welcome to the Microbiome Maverick Podcast, the only place where microbiome science meets real-world applications. I am your host Dr. Amine Zorgani, a microbiome expert on a mission to prevent the human microbiome from extinction!

In this new episode, I have the pleasure of speaking to Dr. Hariom Yadav, Director of University of south Florida center of Microbiome Research. Dr. Hariom is a leading expert in the field of gut microbiome research, with a particular focus on its role in diabetes, aging, and cognitive function. His work has led to significant discoveries in understanding the intricate relationship between diet, gut health, and chronic diseases.

Dr. Hariom's research has revealed that the gut microbiome plays a crucial role in regulating gut permeability, also known as "leaky gut." His study demonstrated that transferring the microbiome from obese mice to lean mice induced leaky gut and inflammation, leading to insulin resistance and increased risk of type 2 diabetes. This finding underscores the importance of maintaining a healthy gut microbiome through proper diet and lifestyle choices.

Furthermore, Dr. Hariom's work explores the gut-brain axis. He emphasizes that the gut harbors as many neurons as the brain, and imbalances in the gut microbiome can contribute to cognitive decline and neurodegenerative disorders. His research aims to develop microbiome-based biomarkers to predict the risk of dementia and Alzheimer's disease, potentially leading to early intervention strategies.

As an entrepreneur, Dr. Hariom has co-founded a company called PostBiotics Inc., which focuses on developing postbiotic-based solutions for reducing leaky gut and inflammation. His innovative approach targets the cellular components of beneficial bacteria, rather than relying solely on live probiotics. This technology has shown promising results in animal studies, demonstrating its potential to improve muscle health, metabolic function, and overall longevity.

Enjoy the episode, and please follow and share! Happy to hear your thoughts and stay positive!

You can find more about Dr Hariom Yadav here: https://www.linkedin.com/in/yadavhariom/

You can find more about The Microbiome Mavericks here: ⁠⁠www.microbiomemavericks.com⁠⁠

If you are interested in speaking, partnering, or sponsoring the show you can reach out directly to ⁠⁠[email protected]⁠⁠