Episode 06: Anesthesia Induction Agents – The Knock Out Bunch!

Anesthesia induction agents are essential anesthesia medications that anesthesia providers need to learn about and understand so they can select the correct medication for the right patient/situation. The primary induction agents used in today’s anesthesia practice include: Propofol, Etomidate, and Ketamine…we refer to these as “The Knock Out Buch!” 

Without a doubt, propofol is used more often than any other anesthesia induction agent. 

In today’s episode, we talk about the pharmacokinetics, pharmacodynamics, mechanism of action, and clinical indications of each one of the anesthesia induction medications. Get ready, because this is an episode filled with key concepts and important information used for exams that is hard to find!

References

1. Nagelhout J, Intravenous Induction Agents. Elisha S, Heiner J, Nagelhout J, eds. Nurse Anesthesia. 7th ed. Elsevier; 2023:101-117.
2. Hailu S, et al. Effectiveness of ketofol versus propofol induction on hemodynamic profiles in adult elective surgical patients: A Randomized Controlled Trial. International Journal of Surgery Open. Vol 37, 2021.
3. Carlson P. Spreading depolarization in acute brain injury inhibited by ketamine: a prospective, randomized, multiple crossover trial. J Neurosurg. 2018 May 25;1-7.
4. Albanese J., et al., Ketamine Decreases Intracranial Pressure and Electroencephalographic Activity in Traumatic Brain Injury Patients during Propofol Sedation . Anesthesiology 1997; 87:1328–1334 doi: https://doi.org/10.1097/00000542-199712000-00011
5. Gregers M., et. al., Ketamine as an Anesthetic for Patients with Acute Brain Injury: A Systematic Review. Neurocrit Care. 2020 Aug;33(1):273-282. doi: 10.1007/s12028-020-00975-7. 

About The Nurse Anesthesia

For anyone who wants to learn or review anesthesia concepts…we will set you up for a successful educational jOURney by providing short, meaningful courses to accelerate your nurse anesthesia learning, tackle your training, and become the successful CRNA you have always dreamed of. Let's do this together. It's Go Time!

Sign up for The Nurse Anesthesia Courses

Learn more about The Nurse Anesthesia at www.thenurseanesthesia.com  

Comments or Suggestions?

We’re here to help you improve your anesthesia learning and practice, and we want to make sure our content is relevant for you. Click here to share your comments and suggestions. 

Legal Disclaimer

The Nurse Anesthesia INC. expressly disclaims any liability in connection with the use of any content in its podcasts, social media posts, and all other published content by any third party.

Music by Alex Grohl 

Mixed & Edited by Next Day Podcast
[email protected]