Recalibration of Early Life Stress Systems: Impact of puberty with Dr. Megan Gunnar

For today's episode, I had the honor of speaking with Dr. Megan Gunnar, a developmental psychologist who discusses her research on early life adversity and stress biology showing the importance of puberty as a window of biological flexibility. Dr. Gunnar discussed work from earlier in her career that led her to pursue these questions through an interdisciplinary lens. Tune in next month to hear more on the importance of adolescence from Dr. Ronald Dahl. 

Dr. Megan Gunnar is a Regents Professor and Distinguished McKnight University Professor at the University of Minnesota. Her doctoral training was in Developmental Psychology at Stanford University. She then completed her post-doctoral fellowship in Psychoneuroendocrinology at Stanford Medical School. Since then, she has built a remarkable career studying how stress biology affects neurobehavioral development and the processes that help children regulate stress hormones. Dr. Gunnar is a fellow of the National Academy of Sciences and has numerous lifetime achievement awards across many societies and disciplines including the Association for Psychological Science and the International Society for Psychoneuroendocrinology. Learn more about Dr. Gunnar's research: https://innovation.umn.edu/gunnar-lab/

Topics Discussed:

• Developmental Psychoneuroendocrinology
• Stress System Calibration and Recalibration
• Stress Reactivity
• Puberty
• Chronic Stress
• HPA Axis
• Early Life Adversity

Papers Mentioned:

• Gunnar, M. R., DePasquale, C. E., Reid, B. M., Donzella, B., & Miller, B. S. (2019). Pubertal stress recalibration reverses the effects of early life stress in postinstitutionalized children. Proceedings of the National Academy of Sciences, 116(48), 23984–23988. https://doi.org/10.1073/pnas.1909699116
• Gunnar, M. R., & Vazquez, D. M. (2001). Low cortisol and a flattening of expected daytime rhythm: Potential indices of risk in human development. Development and Psychopathology, 13(3), 515–538. https://doi.org/10.1017/S0954579401003066
• Engel, M. L., & Gunnar, M. R. (2020). The development of stress reactivity and regulation during human development. International review of neurobiology, 150, 41–76. https://doi.org/10.1016/bs.irn.2019.11.003
• Gunnar, M. R. (2017). Social Buffering of Stress in Development: A Career Perspective. Perspectives on Psychological Science, 12(3), 355–373. https://doi.org/10.1177/1745691616680612

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The Stress Puzzle is hosted by Dr. Ryan L. Brown (https://www.ryanlinnbrown.com/) and supported by the UCSF Stress Measurement Network, an NIH/NIA funded network which aims to better understand the relationship between stress and health by improving the measurement of stress in research studies. Learn more about available resources to support stress research at: www.stressmeasurement.org.

Have burning questions about stress? Email us at [email protected] and we may feature your question in a future episode!