TWiEVO 55: Coronavirus evolution from soup to nuts

Nels and Vincent continue their discussion of SARS-CoV-2 evolution, with a report that the coronavirus proofreading enzyme stimulates RNA recombination, and debunking the conclusion that a change in the viral spike glycoprotein is associated with increased human to human transmission.

Hosts: Nels Elde and Vincent Racaniello

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• CoV proofreading enzyme stimulates recombination (bioRxiv)
• CoV spike mutation pipeline (bioRxiv)
• Issues with CoV sequencing data (virological.org)
• Bill Hanage on selection vs bottleneck (threader.app)
• Image credit
• Time stamps by Jolene. Thanks!

Nels - In Memoriam: Gordon Lark Vincent - John Oliver Discussion of Antibody Tests

Music on TWiEVO is performed by Trampled by Turtles

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