195: Gingipain in the Alzheimer brain

Michael and Vincent discuss the finding of immunity to Cas9 protein in humans, and a potential role for an oral bacterium in Alzheimer’s disease.

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• Immunity to Cas9 protein in humans (Nat Med)
• P. gingivalis and Alzheimer’s disease (Science)
• Clinical trial of COR388 in AD patients (clinicaltrials.gov)
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