TWiM #123: A microbial MAGE

Hosts: Vincent Racaniello, Michael Schmidt, and Elio Schaechter.

Guest: Harris Wang

Harris joins Vincent, Elio, and Michael to describe multiplex automated genome engineering, a method for targeting many modifications in a population of bacterial cells.

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• MAGE - Multiplex automated genome engineering (Nature)
• Genome-scale promoter engineering (Nat Methods)
• Manipulating microbial communities in situ (Trends Genet)
• Engineering human microbiomes (Meth Mol Biol)
• Genome-scale engineering (Mol Syst Biol)
• Economic framework of microbial trade (PLoS One)
• Tardigrade t-shirt
• Image credit

This episode is sponsored by Microbe Magazine Podcast and ASM Microbe 2016

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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