TWiP 178: The shadowlands of medicine

The Knights of the TWiP solve the case of the Man Who Lost Weight, and discuss a Plasmodium protein kinase that is a malarial drug target.

Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin

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Links for this episode

• PWB social media: Facebook, Instagram, Twitter
• Protein kinase as malaria drug target (Science)
• Hero: Myron Schultz
• Letters read on TWiP 178

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Case Study for TWiP 178

Eastern border of Uganda with Kenya, in mountains. Drinking water from nearby stream. Two young boys come to clinic, without parents. Sent in by grandmother because 1 yo brother has been passing worms. Long, white, flat. Shown photos in PD7, pinkish worm, 8 inches long, round. He points to those, what he has been seeing in brother’s stool. 1 year old seems small, protuberant abdomen; brother small for stated age, bit of protuberant belly. Diet: high carbohydrate, flour deep fried; yams; cabbage; some rice; soybeans; pumpkin; bananas.

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Music by Ronald Jenkees