TWiV 1022: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin discusses autochthonous leprosy in the United States, a systematic review to identify novel clinical characteristics of Mpox virus infection and therapeutic and preventive strategies to combat the virus, two-year duration of immunity of inactivated poliovirus vaccine, evaluation of novel oral polio vaccine type 2 SIA impact in a large outbreak of circulating vaccine-derived poliovirus in Nigeria, performance of rapid antigen tests to detect symptomatic and asymptomatic SARS-CoV-2 Infection, effectiveness of the COVID-19 bivalent vaccine, oral Nirmatrelvir and Ritonavir for COVID-19 in vaccinated, non-hospitalized adults ages 18-50 years, genome-wide association study of long COVID, vaccination ameliorates cellular inflammatory responses in SARS-CoV-2 breakthrough infections, and high incidence of autonomic dysfunction and postural orthostatic tachycardia syndrome in patients with long-COVID.

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• Autochthonous leprosy in the United States (NEJM)
• Systematic review to identify novel clinical characteristics of Monkeypox (Archives of Virology)
• Two-year duration of immunity of inactivated poliovirus vaccine (JID)
• Evaluation of novel oral polio vaccine type 2 SIA impact in a outbreak of vaccine-derived poliovirus in Nigeria (IDSA)
• Performance of rapid antigen tests to detect symptomatic and asymptomatic SARS-CoV-2  (AIM)
• Effectiveness of the COVID-19 bivalent vaccine (OFID)
• Oral Nirmatrelvir and Ritonavir for COVID-19 in vaccinated, non-hospitalized adults (CID)
• Genome-wide association study of long COVID (medRxiv)
• Vaccination ameliorates cellular inflammatory responses in SARS-CoV-2 breakthrough infections (JID)
• High incidence of autonomic dysfunction and postural orthostatic tachycardia syndrome in patients with long-COVID (AJM)
• Contribute to our FIMRC fundraiser at PWB
• Letters read on TWiV 1022
• Dr. Griffin’s COVID treatment summary (pdf)
• Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [email protected]