TWiV 353: STING and the antiviral police

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler

The TWiVniacs discuss twenty-eight years of poliovirus shedding by an immunodeficient patient, and packaging of the innate cytoplasmic signaling molecule cyclic GMP-AMP in virus particles.

Links for this episode

• 28 years of poliovirus shedding (PLoS Path) 36:50
• NOT a rare poliovirus (Wash Post) 44:35
• Ukraine polio outbreak (ProMedMail) 41:00
• Virus particle transfer of cGAMP (Science one, two) 47:50
• cGAS on TWiV 222 47:05
• Image credit
• Letters read on TWiV 353 6:30, 1:10:25

This episode is sponsored by ASMGAP 3:10

Timestamps by Jennifer. Thanks!

Weekly Science Picks 1:27:50

Alan - Miniature calendarKathy - Dr. Brainlove (prologue, v. 2.0,  IndieGoGo)Dickson - The Ph.D. MovieVincent - Ghostery

Listener Pick of the Week

Ramon - Children dieChris - ASMLive at ICAAC/ICC

Send your virology questions and comments to [email protected]