TWiV 486: Sean Whelan on being haploid

Sean Whelan returns to TWiV to speak with Vincent about using haploid cell lines to identify genes encoding cell receptors for viruses, including Ebolavirus, Lassa virus, and more.

Host: Vincent Racaniello

Guest: Sean Whelan

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• Ebola virus entry requires the cholesterol transporter Niemann-Pick C1 (Nature)
• Lassa virus entry requires a trigger-induced receptor switch (Science)
• Infectious Entry Pathway Mediated by the Human ERV K Envelope Protein (J Virol)
• Novel Broad-Spectrum Virus Entry Inhibitor (J Virol)
• Mechanism of membrane fusion induced by VSV G protein (PNAS)
• NRP2 and CD63 Are Host Factors for Lujo Virus Cell Entry (Cell Host Micr)
• Image credit

Intro music by Ronald Jenkees

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