TWiV 516: HUSH little virus, don't you transcribe

Lonya and Jeremy take the TWiV team beTWIXt primate immunodeficiency virus proteins Vpx and Vpr and how they counteract transcriptional repression of proviruses by the HUSH complex.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker

Guests: Leonid Yorkovetskiy and Jeremy Luban

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Links for this episode

• Pan American Society for Clinical Virology San Diego and Houston Regional Meetings
• Vpr and Vpx counter HUSH (Nat Micro)
• Vpr and Vpx counter HUSH (bioRxiv version)
• Schematic of HUSH complex (Lehner lab)
• Olive colobus monkey sound credit
• Image credit: William (Ted) Diehl
• Letters read on TWiV 516
• Timestamps by Jolene. Thanks!

Weekly Science Picks

Brianne - The Chimp and the River by David Quammen Rich- James Cook’s First Voyage Journal (20 sec Google Earth summary) Kathy- High resolution Antarctica map NYTimes 46MB Maps (more info and 43 tb maps) Dickson- Jellyfish Jeremy - Pictorial Guide to Living Primates; All The World's PrimatesLonya- Chougui et al. HIV-2/SIV Vpx counters HUSH Vincent - Research!America

Intro music is by Ronald Jenkees.

Send your virology questions and comments to [email protected]