TWiV 522: Readers of the lost ORF

The TWiVsters review isolation of a naturally occurring DNA virus from fruit flies, and the cell-type specific function of a small transmembrane protein encoded in an open reading frame upstream of the enterovirus polyprotein.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Kathy Spindler

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Links for this episode

• Genome-edited babies (Nature)
• Second CRISPR pregnancy? (MIT Tech Rev)
• Naturally occurring DNA virus of Drosophila (PLoS Path)
• Upstream protein coding region in enterovirus genome
• We missed it in 1988! (J Virol)
• Letters read on TWiV 522
• Timestamps by Jolene. Thanks!

Weekly Science Picks

Alan - $40 internationally standard cup of tea Rich- Mars InSight Mission Dickson- New York Botanical Garden Train Show Kathy- Comedy wildlife photo awards finalists Vincent - Senator Gillibrand calls for funding AFM research and our Crowdsourcing of EV-D68 research

Listener Pick

Fernando - Pathfinders by Felipe Fernández-Armesto; Erebus by Michael Palin

Intro music is by Ronald Jenkees.

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