TWiV #74 - Influenza with Professor Adolfo Garcia-Sastre

On episode #74 of the podcast This Week in Virology, Vincent speaks with Adolfo Garcia-Sastre about the origin, pathogenesis, and prevention of the 2009 pandemic influenza H1N1 virus.

Host links Vincent Racaniello and Adolfo Garcia-Sastre

• Influenza virus receptor specificity and disease
• PB1-F2 expression by 2009 H1N1 strain does not increase virulence
• Protection against 2009 H1N1 infection by immunization with older strains
• Passage in eggs changes influenza receptor specificity
• Association between D222G mutation and virulence