TWiV 951: Clinical update with Dr. Daniel Griffin

In his weekly clinical update Dr. Griffin discusses Influenza incidence and vaccine effectiveness during the southern hemisphere influenza season in Chile, Nirsevimab for prevention of RSV infection in healthy late-preterm and term infants, severe Monkeypox in hospitalized patients, reinfections with different SARS-CoV-2 Omicron subvariants, impact of community masking on COVID-19 in Bangladesh, unadjuvanted intranasal spike vaccine elicits protective mucosal immunity against sarbecoviruses, antibody responses to Omicron BA.4/BA.5 bivalent mRNA vaccine booster shot, immunogenicity of bivalent mRNA vaccine boosters, long-term gastrointestinal sequelae following COVID-19, evaluation of an automated text message–based program to reduce use of acute health care resources after hospital discharge, and how in adults with COVID-19, melatonin was assessed for effects on inflammatory markers, clinical signs and symptoms, and mortality.

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• Influenza incidence and vaccine effectiveness (CDC)
• Nirsevimab for prevention of RSV (NEJM)
• Severe Monkeypox in hospitalized patients (CDC)
• Reinfections with different SARS-CoV-2 Omicron subvariants (CDC)
• Impact of community masking on COVID-19 (Science)
• Vaccine elicits protective immunity against sarbecoviruses (Science)
• Antibody responses to bivalent mRNA vaccine booster shot (Biorxiv)
• Immunogenicity of bivalent mRNA vaccine boosters (Biorxiv)
• Long-term gastrointestinal sequelae following COVID-19 (CGH)
• Remdesivir fact sheet for providers (Veklury) 
• Bebtelovimab fact sheet for providers (FDA)
• Evaluation of an automated text message–based program (JAMA)
• Melatonin assessed for effects on inflammatory markers in COVID patients (Heliyon)
• PAXLOVID patient eligibility screening checklist (FDA)
• Contribute to our MicrobeTV fundraiser at PWB
• Dr. Griffin's treatment guide (pdf)
• Letters read on TWiV 951
• Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]