TWiV 976: Clinical update with Dr. Daniel Griffin

In his weekly clinical update Dr. Griffin discusses China reporting almost 60,000 Covid-related deaths after abrupt shift in policy, detection of SARS-CoV-2 IgA and IgG in human milk and breastfeeding infant stool 6 months after maternal COVID-19 vaccination, effect of Fluvoxamine vs placebo on time to sustained recovery in outpatients with mild to moderate COVID-19, hyperimmune globulin for severely immunocompromised patients hospitalized with COVID-19, long COVID outcomes at one year after mild SARS-CoV-2 infection, long COVID: major findings, mechanisms and recommendations, a systematic review of trials currently investigating therapeutic modalities for post-acute COVID-19 syndrome and registered on World Health Organization international clinical trials platform, and the effect of using a structured pacing protocol on post-exertional symptom exacerbation and health status in a longitudinal cohort with the post-COVID-19 syndrome.

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• China records almost 60,000 COVID-related deaths (SCMP)
• Detection of SARS-CoV-2 IgA and IgG in human milk and breastfeeding infant stool (Nature)
• Effect of Fluvoxamine vs placebo in outpatients with COVID-19 (JAMA)
• Hyperimmune Globulin for immunocompromised patients with COVID-19 (JID)
• Long COVID outcomes at one year after mild infection (BMJ) 
• Major findings, mechanisms and recommendations for Long COVID (Nature)
• Review of trials investigating therapeutic modalities for post-acute COVID-19 (CMI)
• Effect of using a structured pacing protocol (JMV)
• Contribute to our MicrobeTV fundraiser at PWB
• Dr. Griffin’s treatment guide (pdf)
• Letters read on TWiV 976
• Don’t crush Paxlovid (pdf)
• Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]