Should you be eating poison oak?

Probably not. But Wall Street Journal reporter Jeff Horwitz decided to try anyway, putting his body — and specifically his butt — on the line to answer a seemingly straightforward question: Is it possible to build up a tolerance to poison oak by eating it?

Guest: Jeff Horwitz, reporter at the Wall Street Journal; and Mahmoud ElSohly, professor of pharmaceutics at the University of Mississippi

For show transcripts, go to vox.com/unxtranscripts

For more, go to vox.com/unexplainable

And please email us! [email protected]

We read every email.

Support Unexplainable by becoming a Vox Member today: vox.com/members

Learn more about your ad choices. Visit podcastchoices.com/adchoices