114 avsnitt • Längd: 20 min • Veckovis: Tisdag
The Go-to Podcast for Biotech Scientists Who Want to Master Bioprocess CMC Development and Manufacturing of Biologics.**TOP 10 LIFE SCIENCES PODCAST**Do you want to simplify bioprocessing so that you can scale with confidence and reduce time to market?Are you sick of feeling overwhelmed by the complexity and guesswork of biologics drug development?Do you wish you had more time to enjoy the beauty of science, without worrying about failing your cell culture process development and commercialization?There’s a way to simplify and streamline so you can remove complexity, skip trials and errors, deliver without delay your groundbreaking therapy to clinics and market, and still enjoy every single step.Hey, I’m David Brühlmann, biotech entrepreneur and consultant, international technology transfer expert, and innovation coach. I’ve been there. And guess what, science may give you headaches, but biologics drug development should not.Want to learn how I and many industry experts did it?- In this podcast, you will learn:- How to develop bioprocesses with peace of mind- How to master biologics drug development- How to deliver your life-transforming therapy to clinics and market fast and efficiently- How to actually enjoy doing all thisI can’t wait to help you do biotech the smart way.Grab a cup of coffee and your favorite notebook and pen. Now is the time to take your bioprocessing game to the next level.Ready? Binge-listen mode: Go!Next Steps:Visit the Website: www.smartbiotechscientist.comEmail us: [email protected]
The podcast Smart Biotech Scientist | Master Bioprocess CMC Development, Biologics Manufacturing & Scale-up for Busy Scientists is created by David Brühlmann: Biotech Entrepreneur & Cell Culture Technology Innovation Aficionado. The podcast and the artwork on this page are embedded on this page using the public podcast feed (RSS).
What do furniture manufacturing and bioprocess weighing have in common? In this fascinating episode, Anders Tvegaard, COO of Eilersen Electric Digital Systems shares the remarkable story of how his company evolved from solving a furniture maker's wood humidity measurement problems to revolutionizing pharmaceutical manufacturing.
Fifty years ago, a simple request to build a more robust scale for weighing wood in sofa production led to the development of groundbreaking contactless load cell technology.
Key takeaways for bioprocess professionals:
From humble beginnings in a Danish basement to transforming modern bioprocessing, this episode reveals how cross-industry innovation is reshaping pharmaceutical manufacturing. Whether you're managing mixing tanks, mobile vessels, or single-use systems, you'll gain valuable insights into improving your bioprocess reliability.
Ready to discover how furniture-inspired technology is solving today's bioprocessing challenges? Tune in now.
Connect with Anders Tvegaard:
LinkedIn: https://www.linkedin.com/in/anders-tvegaard-3305a1
Eilerson: https://eilersen.com
Next Steps:
Wondering how to develop biologics with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? Learn more at https://bruehlmann-consulting.com
Can artificial intelligence revolutionize drug development and reduce the staggering 90% failure rate in clinical trials? In this insightful episode, Lars Brandén, Director of Biology at Kolibri, shares his vision for the future of personalized medicine.
Drawing from his extensive experience bridging academia and industry, Lars explores how AI models could transform our understanding of human disease by simulating body-wide cell signaling. He reveals an innovative approach to drug delivery using receptor ligand combinations that could dramatically reduce side effects and improve treatment efficacy.
Key takeaways:
Ready to dive deeper into the future of biotech innovation? Listen now to unlock Lars Brandén's insights on scaling therapies, navigating cross-functional teams, and maintaining scientific creativity in the face of challenges.
Connect with Lars Brandén:
LinkedIn: https://www.linkedin.com/in/larsbranden
Next Steps:
Wondering how to develop cell and gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at [email protected]
In this episode, we explore the delicate dance between artificial intelligence and biological research with Lars Brandén, Director of Biology at Kolibri. From his early fascination with gene therapy to pioneering high-throughput screening centers at prestigious institutions, Lars shares invaluable insights on bridging the gap between academic innovation and industrial application.
What sets this conversation apart is Lars' compelling perspective on why the popular "agile development" model doesn't always translate smoothly to bioprocess development – and why that matters for the future of drug development. His journey from the Karolinska Institute to leading cutting-edge biological research offers a unique lens on the evolution of biotech.
Key takeaways for listeners:
Join us for this fascinating exploration of how domain expertise and artificial intelligence can work in harmony to accelerate breakthrough therapies. Whether you're a biotech professional or simply curious about the future of medicine, this episode offers valuable insights into the transformation of drug development in the AI era.
Listen now to discover how the intersection of human expertise and artificial intelligence is reshaping the future of personalized medicine.
Connect with Lars Brandén:
LinkedIn: https://www.linkedin.com/in/larsbranden
Next Steps:
Wondering how to develop cell and gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at [email protected]
Could Earth's gentle movements hold the key to scaling up cell therapy production? In this fascinating episode, cellular biologist and entrepreneur Olivier Detournay (CSO of Cellura) reveals how his groundbreaking bioreactor design, inspired by geophysics, is transforming difficult cell culture processes.
By mimicking natural planetary motions, his team at Celura has developed a low-shear stress bioreactor that elegantly solves common scale-up challenges.
Key takeaways for biotech professionals:
Whether you're working in process development or manufacturing, this episode offers invaluable insights into the future of bioprocessing.
Listen now to uncover how looking to nature might help solve your toughest scale-up challenges.
Connect with Olivier Detournay:
LinkedIn: https://www.linkedin.com/in/olivier-detournay-5b157417
Cellura: https://cellura.io
Next Steps:
Wondering how to develop cell and gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO/CSO services. Curious? Learn more at https://bruehlmann-consulting.com
What if the secret to growing sensitive cells lies in mimicking Earth's own movement? In this fascinating episode, cellular biologist Olivier Detournay, CSO of Cellura, reveals how studying planetary motion led to a groundbreaking bioreactor design that could transform cell therapy manufacturing.
Drawing inspiration from geophysics research on magma flows, Olivier and his colleagues developed a revolutionary impeller-free bioreactor that creates gentle, uniform mixing through precise rotation and tilt angles.
Key takeaways for bioprocess scientists:
Whether you're working with stem cells, immunotherapy, or cultivated meat, this episode offers fresh perspectives on overcoming bioprocessing challenges. Join us to explore how nature-inspired solutions could make life-saving cell therapies more accessible.
Connect with Olivier Detournay:
LinkedIn: https://www.linkedin.com/in/olivier-detournay-5b157417
Cellura: https://cellura.io
Next Steps:
Wondering how to develop cell and gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO/CSO services. Curious? Learn more at https://bruehlmann-consulting.com
In this captivating episode, we dive deep into the groundbreaking intersection of artificial intelligence and enzyme engineering with David Schönauer, founder and CEO of Aminoverse.
From university lab benches to pioneering AI-driven enzyme discovery, David shares how his startup is transforming the biotech landscape by making enzyme development faster, more predictable, and increasingly efficient.
Highlights:
David's journey from academic researcher to biotech entrepreneur offers invaluable lessons for scientists considering the entrepreneurial path. His practical approach to combining cutting-edge AI with traditional wet lab techniques demonstrates how modern biotechnology can solve real-world problems while maintaining scientific rigor.
Ready to explore the future of biotech? Listen now to learn how AI is transforming enzyme engineering and what it means for the future of sustainable technology, pharmaceuticals, and more.
Connect with David Schönauer:
LinkedIn: https://www.linkedin.com/in/david-schönauer
Aminoverse: https://www.aminoverse.com
Next Steps:
Wondering how to develop biologics with clarity and precision? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Ready to revolutionize your biologics development? Our Fractional CTO services help you develop better, faster, and more cost-effectively. Leverage your full potential today — book a free consultation at https://bruehlmann-consulting.com and let's accelerate your success!
Ever wondered how scientists find the perfect enzyme among billions of possibilities? In this fascinating episode of the Smart Biotech Scientist podcast, host David Brühlmann sits down with David Schönauer, CEO of Aminoverse, who's revolutionizing enzyme engineering through artificial intelligence.
As a biotech entrepreneur who transformed his academic passion into a groundbreaking startup, Schönauer shares how his company is solving one of biotechnology's biggest challenges: efficiently identifying the right enzyme for specific applications, from pharmaceutical manufacturing to sustainable consumer products.
Key Takeaways:
Whether you're a biotech professional or simply curious about the intersection of AI and biotechnology, this episode reveals how cutting-edge technology is accelerating the discovery of nature's molecular workers.
Ready to explore the future of enzyme engineering? Tune in now to hear how AI is transforming biotech innovation, one enzyme at a time.
Connect with David Schönauer:
LinkedIn: https://www.linkedin.com/in/david-schönauer
Aminoverse: https://www.aminoverse.com
Next Steps:
Wondering how to develop biologics with clarity and precision? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Ready to revolutionize your biologics development? Our Fractional CTO services help you develop better, faster, and more cost-effectively. Leverage your full potential today — book a free consultation at https://bruehlmann-consulting.com and let's accelerate your success!
In this insightful episode, Technical Development Leader at Flagship Pioneering Oliver Kraemer reveals why developing Advanced Therapy Medicinal Products (ATMPs) require a fundamental shift in thinking from traditional biologics development.
Drawing from his extensive experience across Boehringer Ingelheim, Sanofi, and BMS, Kraemer challenges conventional wisdom about process development timing and demonstrates why early integration of process considerations is crucial for ATMP success.
You will learn:
Ready to transform your approach to ATMP development? Join us for this must-listen episode as we demystify the path from bench to bedside in cell and gene therapy.
Connect with Oliver Kraemer:
LinkedIn: https://www.linkedin.com/in/oliver-kraemer
Next Steps:
Wondering how to develop cell and gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop cell and gene therapies better, faster, at a fraction of the cost with our Fractional CTO services. Curious? Learn more at https://bruehlmann-consulting.com
In this eye-opening episode, we explore the intricate landscape of Advanced Therapy Medicinal Products (ATMPs) with Oliver Kraemer, a technical development leader at Flagship Pioneering.
Drawing from his extensive experience at industry giants like BMS, Sanofi, and Boehringer Ingelheim, Oliver challenges conventional wisdom about automation in cell and gene therapy while illuminating the crucial differences between biologics and ATMPs.
Key Takeaways for Biotech Scientists:
Join us as Oliver shares invaluable insights from his journey from traditional biologics to cutting-edge cell therapies, including both iPSC-derived and donor-derived approaches. Whether you're a bioprocess developer, cell therapy researcher, or biotech professional, this episode offers practical wisdom for navigating the complex landscape of ATMP development.
Ready to transform your understanding of cell therapy development? Listen now to gain insights that could save you months or even years in your development timeline.
Connect with Oliver Kraemer:
LinkedIn: https://www.linkedin.com/in/oliver-kraemer
Next Steps:
Wondering how to develop cell and gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop cell and gene therapies better, faster, at a fraction of the cost with our Fractional CTO services. Curious? Learn more at https://bruehlmann-consulting.com
Want to peek behind the curtain of a leading Contract Development and Manufacturing Organization (CDMO)? In this inspiring episode, KBI Biopharma's Chief Scientific Officer Sigma Mostafa reveals the intricate world of bioprocess development and manufacturing.
Sigma shares game-changing insights into accelerating biologics development without compromising quality. She also unveils how KBI is leveraging AI and machine learning to revolutionize everything from protein sequence analysis to formulation development.
Key Takeaways:
Ready to transform your bioprocess development journey? Tune in to hear Sigma's vision for the future of CDMOs and get actionable insights for your next project.
Connect with Sigma Mostafa:
Linkedin: https://www.linkedin.com/in/sigma-mostafa-79180817
KBI: https://www.kbibiopharma.com
Next Steps:
Wondering how to fast-track bioprocess CMC development? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics at a fraction of the cost with our Fractional CTO services. Curious? DM us at https://bruehlmann-consulting.com
In this insightful episode, we're joined by Sigma Mostafa, Chief Scientific Officer at KBI Biopharma, who shares crucial insights on selecting the right CDMO partner for biotech development.
Sigma brings a unique blend of scientific rigor and practical experience to the discussion, having worked on both sides of the CDMO relationship.
Key Takeaways:
Sigma emphasizes that successful CDMO partnerships hinge on transparent communication and cultural alignment, not just technical capabilities. She reveals that while one-stop shops seem convenient, partnering with specialized CDMOs who excel in specific areas often yields better results - as long as there's strong project coordination.
Whether you're a startup navigating your first CDMO relationship or an established biotech company looking to optimize your partnerships, this episode provides actionable insights for making informed decisions that will impact your project's success for years to come.
Listen now to transform your approach to CDMO selection and avoid costly pitfalls in your bioprocess development journey.
Connect with Sigma Mostafa:
Linkedin: https://www.linkedin.com/in/sigma-mostafa-79180817
KBI: https://www.kbibiopharma.com
Next Steps:
Wondering how to fast-track bioprocess CMC development? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics at a fraction of the cost with our Fractional CTO services. Curious? DM us at https://bruehlmann-consulting.com
Struggling to unravel the complexities of your bioprocess? Prepare for a paradigm shift as we dive into the world of Process Analytical Technology (PAT) with Katharina Dahlmann who is Application and PAT Expert at Hamilton.
This eye-opening episode dissects how PAT is redefining biologics manufacturing, balancing its immense potential against real-world implementation hurdles. Katharina navigates us through the intricate journey of scaling up, from micro-bioreactors to large-scale bioreactors, unveiling the hidden gems of early PAT adoption. Whether you're a startup scientist or a seasoned biotech veteran, this episode is packed with insights to elevate your bioprocessing game.
Tune in to uncover:
Don't let bioprocess complexity hold you back – listen now and harness the power of PAT to decode your processes like never before!
Connect with Katharina Dahlmann:
LinkedIn: https://www.linkedin.com/in/dr-katharina-dahlmann-616790180
Hamilton: https://www.hamiltoncompany.com
Next Steps:
Wondering how to develop biologics with clarity and precision? Schedule your free consultation to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? Contact us at https://bruehlmann-consulting.com
Unlock the hidden potential of your bioprocess! In this eye-opening episode, David Brühlmann sits down with Katharina Dahlmann, Application and PAT Expert at Hamilton, to explore the game-changing world of Process Analytical Technology (PAT).
Discover how PAT is revolutionizing biotech by providing unprecedented insights into cell behavior and process dynamics. Katharina challenges conventional wisdom, revealing that what we think we know about our processes may just be the tip of the iceberg. Learn how combining multiple PAT signals can extract meaningful knowledge, leading to more reproducible and efficient processes.
You will gain valuable insights on:
Ready to take your bioprocessing game to the next level? Tune in now and transform your approach to bioprocess monitoring and control!
Connect with Katharina Dahlmann:
LinkedIn: https://www.linkedin.com/in/dr-katharina-dahlmann-616790180
Hamilton: https://www.hamiltoncompany.com
Next Steps:
Wondering how to develop biologics with clarity and precision? Schedule your free consultation to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? Contact us at https://bruehlmann-consulting.com
Imagine predicting your bioprocess outcomes as easily as checking the weather forecast. Sound impossible? Not anymore. In this insightful episode, we dive deep into the world of digital twins and process models with Fabian Feidl, co-founder and CTO of DataHow.
Discover how these cutting-edge tools are reshaping the biotech landscape, from simplifying complex processes to enabling personalized medicine. Fabian shares invaluable insights on implementing data-driven approaches, even for smaller companies with limited resources.
Key takeaways:
Ready to revolutionize your biotech workflow? Tune in now and unlock the secrets to smarter, more efficient bioprocessing!
Connect with Fabian Feidl:
LinkedIn: https://www.linkedin.com/in/fabian-feidl-a52b36b3
DataHow: https://datahow.ch
Next Steps:
Wondering how to develop biologics with clarity and precision? Schedule your free consultation to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? Contact us at https://bruehlmann-consulting.com
Are you ready to decode the future of bioprocessing? In this eye-opening episode, we dive deep into the world of digital bioprocess development with Fabian Feidl, co-founder and CTO of DataHow.
Discover how cutting-edge process models are transforming the biotech industry, bridging the gap between raw data and actionable insights.
Key takeaways:
From optimizing experimental design to enabling data-driven decision-making, this episode is packed with invaluable insights for biotech scientists and leaders. Tune in now to unlock the future of bioprocessing and take your research to the next level!
Connect with Fabian Feidl:
LinkedIn: https://www.linkedin.com/in/fabian-feidl-a52b36b3
DataHow: https://datahow.ch
Next Steps:
Wondering how to develop biologics with clarity and precision? Schedule your free consultation to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? Contact us at https://bruehlmann-consulting.com
Are you ready to dive into the cutting-edge world of biomanufacturing? In this episode, strategic consultant James Ryall unveils the staggering potential of bio-based products to revolutionize industries. From cultured meat to human breast milk, discover how cells are becoming the ultimate manufacturing facilities.
James shares invaluable insights on scaling challenges, regulatory hurdles, and the critical importance of early preparation for biotech startups. Learn why biomanufacturing is poised to transform up to 60% of consumer goods and how to stay ahead in this rapidly evolving field.
Gain expert strategies to:
Whether you're a seasoned bioprocessing expert or a curious entrepreneur, this episode will ignite your passion for the biotech revolution. Tune in now and discover how to ride the wave of biomanufacturing innovation!
Connect with James Ryall:
LinkedIn: https://www.linkedin.com/in/james-ryall
Website: https://www.jamesryall.com
Next Steps:
Wondering how to develop biologics with clarity and precision? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? Contact us at https://bruehlmann-consulting.com
In this captivating episode, host David Brühlmann welcomes James Ryall, a strategic consultant with over two decades of experience in cell biology and regenerative medicine. From his groundbreaking work in skeletal muscle research to revolutionizing cultured meat production, James shares his fascinating journey through academia and industry.
Discover how he's now helping biotech startups align their technical strategies with commercial outcomes, accelerating their path to market.
You will gain invaluable insights on:
Don't miss this eye-opening discussion on simplifying bioprocessing and bringing game-changing products to life. Tune in now to supercharge your biotech career!
Connect with James Ryall:
LinkedIn: https://www.linkedin.com/in/james-ryall
Website: https://www.jamesryall.com
Next Steps:
Wondering how to develop biologics with clarity and precision? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? Contact us at https://bruehlmann-consulting.com
Are you ready to revolutionize your bioprocess development? Join David Brühlmann as he interviews Belma Alispahic, Chief Scientific Officer and Co-Founder of AnalysisMode, who unveils the game-changing potential of AI in biopharma.
Discover how AI is transforming the industry, from drug discovery to manufacturing, and learn why it's no longer optional but essential for success.
Key takeaways:
Don't miss this opportunity to stay ahead of the curve and unlock the full potential of your biotech projects. Tune in now to empower your scientific journey and simplify complex bioprocessing challenges with AI-driven solutions.
Connect with Belma Alispahic:
LinkedIn: https://www.linkedin.com/in/balispahic
Analysis Mode: https://analysismode.com
Next Steps:
Wondering how to develop biologics with clarity and precision? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? Contact us at https://bruehlmann-consulting.com
Is AI the secret weapon biotech scientists have been waiting for? In this eye-opening episode, we dive deep into the world of AI-driven bioprocess development with Belma Alispahic, Chief Scientific Officer and Co-Founder of AnalysisMode. Discover how AI is transforming the biotech landscape, from reducing downtime by 50% to unlocking unprecedented levels of precision in process optimization.
Key takeaways:
Don't miss this game-changing discussion that could revolutionize your approach to bioprocess development. Tune in now and stay ahead of the curve in the rapidly evolving world of biotech!
Connect with Belma Alispahic:
LinkedIn: https://www.linkedin.com/in/balispahic
Analysis Mode: https://analysismode.com
Next Steps:
Wondering how to develop biologics with clarity and precision? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? Contact us at https://bruehlmann-consulting.com
In this electrifying episode, we dive deep into the future of biotech with biotech influencer Benjamin McLeod. From quantum AI mapping cellular interactions to the game-changing potential of process analytical technology, Ben, who is also a Cell & Gene Therapy Segment Lead at NanoMosaic, unveils how artificial intelligence is set to transform the cell and gene therapy landscape.
Discover why LinkedIn is becoming the new frontier for biotech networking and career advancement. Learn how combining AI with PAT could slash production costs and boost yields in ways you've never imagined.
You will gain invaluable insights on:
Don't miss this opportunity to stay ahead of the curve in biotech innovation. Tune in now and revolutionize your approach to bioprocessing!
Connect with Benjamin McLeod:
LinkedIn: https://www.linkedin.com/in/benjamin-mcleod
NanoMosaic: https://www.nanomosaicllc.com
Next Steps:
Wondering how to develop cell and gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at [email protected]
Discover how a failed optometry dream led Benjamin McLeod to become a leading voice in cell and gene therapy. In this eye-opening episode, Ben, who is a Cell & Gene Therapy Segment Lead at NanoMosaic, shares his unconventional path from lab work to LinkedIn stardom, revealing how he bridges the gap between R&D and marketing in biotech.
Learn how Ben's weekly science memes evolved into valuable content that attracts both lab techs and CEOs alike.
Key takeaways:
Whether you're a seasoned scientist or biotech enthusiast, this episode offers invaluable insights into the art of scientific communication. Tune in now to transform your approach to biotech development and communicating science.
Connect with Benjamin McLeod:
LinkedIn: https://www.linkedin.com/in/benjamin-mcleod
NanoMosaic: https://www.nanomosaicllc.com
Next Steps:
Wondering how to develop cell and gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at [email protected]
Ever wondered why your perfectly optimized lab process falls apart at industrial scale?
Mass transfer experts Lars Puiman and Rik Volger from the University of Delft reveal the hidden world of oxygen transfer and aeration that can make or break your production.
Dive into the crucial differences between lab-scale and industrial-scale bioreactors, and discover why your DO sensor might be fooling you. Learn how CFD simulations and innovative downscaling techniques can revolutionize your scale-up strategy.
In this episode, you'll gain:
From the basics of bubble behavior to the latest in AI and machine learning, this episode is packed with practical insights to enhance your bioprocess efficiency and product quality. Don't miss out on these game-changing mass transfer secrets – tune in now and take your bioprocessing skills to the next level!
Connect with our guests:
Lars Puiman: https://www.linkedin.com/in/larspuiman
Rik Volger: https://www.linkedin.com/in/rikvolger
Next Step:
Enhance your bioprocess development strategy! Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Additional Resources:
Bubbles and Broth: A review on the impact of broth composition on bubble column bioreactor hydrodynamics
Read the review paper at https://doi.org/10.1016/j.bej.2023.109124
Unlock the mysteries of oxygen transfer in bioreactors with mass transfer experts Lars Puiman and Rik Volger from the University of Delft. In this eye-opening episode, dive deep into the crucial world of kLa (oxygen mass transfer coefficient) and its impact on bioprocess scale-up.
Discover why understanding kLa is essential for optimizing cell growth and product formation in bioreactors. Learn practical strategies to enhance oxygen transfer, from manipulating bubble size to leveraging unexpected allies like ethanol. Our experts reveal:
Whether you're a seasoned bioprocess engineer or a curious scientist, this episode will revolutionize your approach to oxygen transfer in bioprocessing.
Don't miss these game-changing insights – tune in now!
Connect with our guests:
Lars Puiman: https://www.linkedin.com/in/larspuiman
Rik Volger: https://www.linkedin.com/in/rikvolger
Next Step:
Enhance your bioprocess development strategy! Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Additional Resources:
Bubbles and Broth: A review on the impact of broth composition on bubble column bioreactor hydrodynamics
Read the review paper at https://doi.org/10.1016/j.bej.2023.109124
Dive into the cutting-edge world of gene therapy as we unravel the complexities of AAV production. In this insightful episode, Ahmed Youssef, a seasoned AAV expert and Senior Process Development Manager at Ascend, explains how you can navigate the complex world of AAV scale-up and learn why thinking outside the box is crucial for success.
Key takeaways:
From plasmid alternatives to cutting-edge CDMO strategies, this episode is packed with game-changing information. Don't miss out on these invaluable scale-up secrets that could transform your gene therapy projects.
Tune in now and take your AAV production skills to the next level!
Connect with Ahmed Youssef:
LinkedIn: https://www.linkedin.com/in/ahmed-samir-youssef
Ascend: https://www.ascend-adv.com
Next Steps:
Wondering how to develop cell and gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at [email protected]
Unlock the mysteries of AAV manufacturing in this eye-opening episode! Ahmed, a seasoned AAV expert and Senior Process Development Manager at Ascend, reveals insider strategies for biotech scientists navigating the complex world of gene therapy production.
Discover why quality is the cornerstone of successful AAV development and how to avoid costly missteps in the journey from lab to clinic.
Key takeaways:
From cell line selection to plasmid optimization, Ahmed breaks down the critical factors that can make or break your AAV project. Whether you're a biotech novice or a seasoned pro, this episode is packed with actionable advice to elevate your gene therapy game.
Ready to revolutionize your approach to AAV production? Tune in now!
Connect with Ahmed Youssef:
LinkedIn: https://www.linkedin.com/in/ahmed-samir-youssef
Ascend: https://www.ascend-adv.com
Next Steps:
Wondering how to develop cell and gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at [email protected]
Unlock the secret weapon of biotech success! In this eye-opening episode, host David Brühlmann reveals how fractional CTOs are revolutionizing drug development, inspired by Michael Jordan's approach to greatness. Learn how this innovative strategy can slash timelines, mitigate risks, and give your biotech company a competitive edge.
Discover the game-changing benefits of fractional expertise:
Ready to transform your biotech journey? Tune in to explore how harnessing fractional expertise could be the catalyst your company needs.
Don't miss this opportunity to level up your drug development game – listen now and stay ahead in the fast-paced world of biotech innovation!
Next Steps:
Schedule your free call at https://bruehlmann-consulting.com/assessment to discover how you can develop biologics better, faster, at a fraction of the cost with our Fractional CTO services.
Unlock the secrets of successful bioprocess development with host David Brühlmann as he shares hard-won lessons from his 15+ years of experience leading technology transfers and technology innovation projects.
Discover why prioritizing process development is crucial for transforming groundbreaking science into life-changing therapies. In this eye-opening episode, you'll learn:
From selecting the right cell lines to mastering the delicate dance of speed and quality, David unveils the hidden pitfalls that can derail even the most promising biotech innovations.
Whether you're a seasoned scientist or a curious entrepreneur, this episode is packed with actionable insights to supercharge your bioprocess development. Don't miss out – tune in now and take your biotech game to the next level!
Next Steps:
Wondering how to develop biologics with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at https://bruehlmann-consulting.com
What if your biomanufacturing facility could run itself, optimize its own processes, and operate non-stop? This isn't science fiction – it's the cutting-edge reality Professor Massimo Morbidelli is helping to create.
In this captivating episode, the bioprocessing pioneer unveils how AI, continuous manufacturing, and revolutionary machine learning techniques are transforming the industry landscape.
As a Professor Emeritus at ETH Zurich and Politecnico di Milano, and a co-founder of ChromaCon (now YMC) and DataHow, Massimo Morbidelli has been at the forefront of bioprocess innovation. He is currently the recipient of the ERC Advanced Grant Continuous Digitalisation of Bioprocesses (CoDiBio) at the Aristotle University of Thessaloniki.
Discover how transfer learning is revolutionizing process development across molecules and scales, dramatically reducing time-to-market for new biologics. Learn why the integration of computer science and biology is crucial for staying competitive in the rapidly evolving biopharma landscape.
You will gain invaluable insights on
All are essential skills for thriving in the next era of biomanufacturing.
Tune in now and revolutionize your approach to biopharma innovation!
Connect with Massimo Morbidelli:
Email: massimo “dot” morbidelli “at” polimi “dot” it
Next Steps:
Wondering how to develop biologics with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? Contact us at https://bruehlmann-consulting.com
Imagine a world where biologic drugs are produced faster, cheaper, and with unprecedented precision.
In this episode, we dive into that future with Professor Massimo Morbidelli, a trailblazer in bioprocessing innovation. As a Professor Emeritus at ETH Zurich and Politecnico di Milano, and a co-founder of ChromaCon (now YMC) and DataHow, Massimo Morbidelli has been at the forefront of bioprocess innovation. He is currently the recipient of the ERC Advanced Grant Continuous Digitalisation of Bioprocesses (CoDiBio) at the Aristotle University of Thessaloniki.
From his groundbreaking work in continuous chromatography to spearheading AI-driven manufacturing, Morbidelli's 25-year journey has reshaped the biotech landscape.
Discover how initial industry skepticism transformed into widespread adoption of continuous processing and machine learning. Prof. Morbidelli shares insights on his current project: a fully automated, end-to-end manufacturing process for plasmid DNA production.
You will gain invaluable insights into:
Don't miss this opportunity to learn from a true visionary in the field.
Tune in now to unlock the secrets of next-generation biomanufacturing and stay ahead of the curve in this rapidly evolving industry.
Connect with Massimo Morbidelli:
Email: massimo “dot” morbidelli “at” polimi “dot” it
Next Steps:
Wondering how to develop biologics with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? Contact us at https://bruehlmann-consulting.com
Are your shake flasks holding back your bioprocess development? Discover how to transform them into smart bioreactors! In this game-changing episode, we talk with Jens Bayer about the groundbreaking DOTS platform. He is a deep tech entrepreneur and seasoned commercial leader, currently serving as Chief Commercial Officer at Scientific Bioprocessing.
Jens reveals how this cutting-edge technology is bridging the gap between simple shake flasks and complex bioreactors, offering scientists unprecedented control and data insights.
Learn how to:
Whether you're a startup scientist or working in Big Pharma, this episode will revolutionize your approach to early-stage bioprocessing. Don't miss Jens' invaluable tips for designing successful shake flask experiments and his inspiring journey as a biotech entrepreneur.
Ready to supercharge your bioprocess development? Tune in now and unlock the hidden potential of your shake flasks!
Connect with Jens Bayer:
LinkedIn: https://www.linkedin.com/in/jens-bayer-65a46350
Scientific Bioprocessing: https://www.scientificbio.com
Next Steps:
Wondering how to develop biologics with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at https://bruehlmann-consulting.com
Are shake flasks outdated relics or untapped goldmines of bioprocess development? In this eye-opening episode, we dive deep with Jens Bayer, a deep tech entrepreneur and seasoned commercial leader, currently serving as Chief Commercial Officer at Scientific Bioprocessing.
Jens shatters common misconceptions about shake flasks, revealing why they remain indispensable tools in both industry and research settings.
Discover:
From startups to Big Pharma, learn how mastering shake flask techniques can accelerate your bioprocess development and save precious resources. Whether you're a seasoned biotech pro or just starting out, this episode will transform how you approach early-stage bioprocessing.
Ready to revolutionize your lab work? Tune in now and unlock the hidden potential of shake flasks!
Connect with Jens Bayer:
LinkedIn: https://www.linkedin.com/in/jens-bayer-65a46350
Scientific Bioprocessing: https://www.scientificbio.com
Next Steps:
Wondering how to develop biologics with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at https://bruehlmann-consulting.com
Dive into the cutting-edge world of autologous cell-based therapy with Deana Mohr, CEO and co-founder of MUVON Therapeutics, spin-off from the University of Zurich. In this eye-opening episode, discover how MUVON Therapeutics’ innovative approach to muscle regeneration is revolutionizing treatments for stress urinary incontinence and beyond.
Learn how her team is tackling the challenges of bringing personalized medicine to market at scale, from navigating complex regulations to automating production processes.
Listeners will gain invaluable insights on:
Whether you're a scientist, investor, or healthcare professional, this episode offers a fascinating glimpse into the future of regenerative medicine. Tune in to explore how Deana's vision of "copy-paste" therapy production could transform millions of lives and reshape the biotech landscape!
Connect with Deana Mohr:
LinkedIn: https://www.linkedin.com/in/deana-mohr-haralampieva-95a9a5a4
MUVON Therapeutics: https://www.muvon-therapeutics.com
Next Steps:
Wondering how to develop cell and gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at [email protected]
Discover how scientists are transforming lives through innovative muscle regeneration therapy. In this captivating episode, Deana Mohr, CEO and co-founder of MUVON Therapeutics, spin-off from the University of Zurich, unveils her groundbreaking autologous muscle regeneration technology for treating stress urinary incontinence.
Learn how this minimally invasive treatment harnesses the power of a patient's own cells to restore muscle function, offering hope to millions. Diana shares her journey from PhD research to clinical trials, revealing the challenges of translating cutting-edge science into real-world treatments.
Listeners will gain insights on:
Whether you're a scientist, investor, or simply curious about medical innovations, this episode offers a fascinating glimpse into the future of regenerative medicine. Tune in to explore the forefront of biotech entrepreneurship!
Connect with Deana Mohr:
LinkedIn: https://www.linkedin.com/in/deana-mohr-haralampieva-95a9a5a4
MUVON Therapeutics: https://www.muvon-therapeutics.com
Next Steps:
Wondering how to develop cell and gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at [email protected]
Ever wondered why some biotech facilities thrive while others struggle Alfredo Martínez Mogarra, a Bioprocess Engineer with over 30 years of experience and Chief Operations Manager at VIVEbiotech, reveals the secrets to successful biotech manufacturing.
In this eye-opening episode, Alfredo shares critical insights on bridging the gap between lab-scale processes and industrial production.
You will get:
Whether you're a biotech scientist, engineer, or industry professional, this episode is packed with invaluable wisdom to elevate your facility design and operations.
Don't miss Alfredo's golden rule: "Think very well before starting doing things." Tune in now and learn how to build a foundation for biotech success!
Connect with Alfredo Martínez Mogarra:
LinkedIn: https://www.linkedin.com/in/alfredo-martínez-mogarra-a381087
Biotech Academy in Rome: https://www.biotechacademy.eu
Next Steps:
Wondering how to develop biologics with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at https://bruehlmann-consulting.com
Ever wondered what it takes to build a large-scale biotech manufacturing facility? Alfredo Martínez Mogarra, a seasoned Bioprocess Engineer with over 30 years of experience and Chief Operations Manager at VIVEbiotech, reveals the secrets behind successful biotech facility design and scale-up. He has been at the forefront of transforming bench processes into industrial realities.
In this eye-opening episode, Alfredo shares critical insights on navigating the complex world of biotech manufacturing. Listeners will gain:
Whether you're a biotech scientist, engineer, or industry professional, this episode is packed with invaluable wisdom to elevate your bioprocessing game.
Tune in now and learn how to think holistically about biotech facility design.
Connect with Alfredo Martínez Mogarra:
LinkedIn: https://www.linkedin.com/in/alfredo-martínez-mogarra-a381087
Biotech Academy in Rome: https://www.biotechacademy.eu
Next Steps:
Wondering how to develop biologics with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at https://bruehlmann-consulting.com
Unlock the secrets of cell factories and discover how cutting-edge technologies are revolutionizing biopharmaceutical production. In this episode, we welcome Mauro Torres, a postdoctoral researcher at the University of Manchester, who takes us on a fascinating journey through the complex world of protein manufacturing.
Mauro Torres explains the intricate steps involved in the secretory pathway, from gene expression to protein export, likening it to a sophisticated car manufacturing process. He then delves into how omics technologies and systems-level approaches are enhancing our understanding of cell physiology and improving production effectiveness.
Listeners will gain valuable insights into:
Discover how these advancements are paving the way for more predictable, affordable, and robust medicine production, promising a brighter future for patients worldwide.
Connect with Mauro Torres:
Linkedin: https://www.linkedin.com/in/mauro-torres-seb
Next Steps:
Book a free assessment to help you develop biologics with peace of mind: https://bruehlmann-consulting.com
Unlock the secrets of cell factories with Mauro Torres, a postdoctoral researcher at the University of Manchester who brings cutting-edge insights into protein production. Discover how the concept of cell factories has evolved from basic insulin extraction to groundbreaking treatments for genetic disorders and cancer. We reveal the challenges faced by biotech scientists in bioprocess development and offers a fascinating analogy between car manufacturing and cellular protein assembly.
Learn how recent advancements in synthetic biology, genetic editing, and AI-driven process optimization are transforming the biopharmaceutical industry. From transposon technology to microfluidics and hybrid modeling, We explore the game-changing innovations that are accelerating cell line development and enhancing protein secretion.
Gain valuable insights into:
Don't miss this episode packed with expert knowledge on the future of biomanufacturing.
Connect with Mauro Torres:
Linkedin: https://www.linkedin.com/in/mauro-torres-seb
Next Steps:
Book a free assessment to help you develop biologics with peace of mind: https://bruehlmann-consulting.com
Curious about the latest innovations in cell analysis technology? Join us in this episode with Furkan Gökçe, New Business Development Manager at Amphasys, as we delve into the fascinating world of Impedance Flow Cytometry (IFC).
Furkan shares how IFC is revolutionizing single-cell analysis by providing faster, more precise, and high-resolution data.
Key Takeaways:
Tune in to uncover how IFC is set to transform the landscape of bioprocessing, ensuring better quality and sustainability in biologics production.
Connect with Furkan Gökçe:
LinkedIn: https://www.linkedin.com/in/furkangokce
Amphasys: https://amphasys.com/bioprocessing
Next Steps:
Book a free assessment to help you get started with the implementation of new technologies in your manufacturing processes: https://bruehlmann-consulting.com
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at [email protected]
Ever wondered how single-cell analysis could revolutionize bioprocessing? Join us in this episode as we delve into the cutting-edge world of impedance flow cytometry.
Furkan Gökçe, New Business Development Manager at Amphasys, shares his insights on the transformative power of this technology in the biotech industry. With a background in engineering and physics, Furkan provides a unique perspective on tackling the complexities of biological systems.
Key Takeaways:
Tune in to gain valuable knowledge on how this innovative technology can enhance your bioprocess development and manufacturing strategies!
Connect with Furkan Gökçe:
LinkedIn: https://www.linkedin.com/in/furkangokce
Amphasys: https://amphasys.com/bioprocessing
Next Steps:
Book a free assessment to help you get started with the implementation of new technologies in your manufacturing processes: https://bruehlmann-consulting.com
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at [email protected]
Dive into the transformative world of bead-based assays with Sebastian Giehring, CEO and founder of PAIA Biotech, where high-throughput screening meets cutting-edge biotechnological advancements.
Join us as we chat with Sebastian, a seasoned scientist and entrepreneur who has revolutionized the workflow of high-throughput screening of titer, glycosylation, and aggregation with innovative bead-based assays.
Key Takeaways:
Tune in to uncover how these insights can transform your lab's capabilities and drive groundbreaking discoveries!
Connect with Sebastian Giehring:
LinkedIn: https://www.linkedin.com/in/sebastian-giehring-6ba1992
PAIA Biotech: https://www.paiabio.com
Next Steps:
Book a free assessment to help you get started with the design of your next experiment at https://bruehlmann-consulting.com
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at [email protected]
Ready to revolutionize your lab work? Join us as we dive deep into bead-based assays with Sebastian Giehring, CEO and founder of PAIA Biotech.
Discover how these tiny beads are making a massive impact on biotech research and development — for titer, glycan, and aggreation screening — and how this developability screening platform can enhance your antibody discovery, antibody engineering and lead optimization.
In this episode, you’ll learn:
Tune in to uncover how these assays can transform your biotech research and push the boundaries of what's possible!
Connect with Sebastian Giehring:
LinkedIn: https://www.linkedin.com/in/sebastian-giehring-6ba1992
PAIA Biotech: https://www.paiabio.com
Next Steps:
Book a free assessment to help you get started with the design of your next experiment at https://bruehlmann-consulting.com
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at [email protected]
How do small biotech companies make strategic decisions with limited resources? This episode dives deep into the art of prioritization and outsourcing to achieve success.
Join us as we speak with Mark Melville, Vice President of CMC, Biologics at Cullinan Therapeutics, a seasoned biotech scientist with years of experience in both large and small biotech companies. Mark shares his invaluable insights on navigating the complexities of bioprocess development and outsourcing.
In this episode, we explore:
Connect with Mark Melville:
LinkedIn: https://www.linkedin.com/in/mark-melville-a9a43b2
Next Steps:
Wondering how to develop biologics with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at https://bruehlmann-consulting.com
Are you navigating the complex world of bioprocess CMC development and manufacturing in a small biotech company?
Our latest episode is a must-listen! Join us as we sit down with Mark Melville, Vice President of CMC, Biologics at Cullinan Therapeutics, who shares invaluable insights on overcoming the unique challenges faced by small biotech firms.
In this episode, we explore:
Tune in to discover how mastering these areas can help your small biotech thrive and stay ahead in a competitive market.
Don't miss this opportunity to gain practical advice and turn your challenges into advantages!
Connect with Mark Melville:
LinkedIn: https://www.linkedin.com/in/mark-melville-a9a43b2
Next Steps:
Wondering how to develop biologics with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at https://bruehlmann-consulting.com
In this insightful episode, we explore the cutting-edge field of glycoengineering and its transformative impact on biopharmaceutical drug design. Join us as we chat with Róisín O’Flaherty, Assistant Professor in the Department of Chemistry at Maynooth University, to uncover the nuances of chemoenzymatic glycogen engineering and its potential to revolutionize therapeutics.
Key Takeaways:
Don't miss this deep dive into how glycoanalytics is paving the way for more effective and personalized biopharmaceutical drugs. Tune in to understand the future of drug design and the exciting possibilities it holds.
Connect with Róisín O’Flaherty:
LinkedIn: https://www.linkedin.com/in/roisin-o-flaherty-a67a2b8a
Twitter: https://x.com/irishglycogirl
Next Steps:
Book a free assessment to help you get started with glycoanalytics and glycoengineering at https://bruehlmann-consulting.com
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at [email protected]
Uncover the hidden science behind creating safer, more effective biological drugs! Dive into glycoanalytics and glycoengineering, the secret weapons revolutionizing biopharma.
Join us as we talk with Róisín O’Flaherty, Assistant Professor in the Department of Chemistry at Maynooth University, who breaks down the complexities of glycosylation and its pivotal role in drug development.
Key Takeaways:
Tune in to explore how glycoanalytics is driving the next generation of safer, more effective biopharmaceuticals!
Connect with Róisín O’Flaherty:
LinkedIn: https://www.linkedin.com/in/roisin-o-flaherty-a67a2b8a
Twitter: https://x.com/irishglycogirl
Next Steps:
Book a free assessment to help you get started with glycoanalytics and glycoengineering at https://bruehlmann-consulting.com
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at [email protected]
Join us as we explore the pivotal role of process mapping in biotech knowledge management. Our guest, Irwin Hirsh, a seasoned biotech consultant concentrating on enhancing business efficiency and effectiveness, shares invaluable insights into leveraging technology to streamline operations.
Key Insights:
Join us as Irwin uncovers actionable steps to enhance efficiency and innovation in biotech through strategic process mapping.
Connect with Irwin Hirsh:
LinkedIn: https://www.linkedin.com/in/ishirsh
Q-Specialists AB: https://www.qspecialists.com
Next Steps:
Wondering how to develop biologics and cell & gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at https://bruehlmann-consulting.com
Want to turn your biotech chaos into streamlined success? Learn from expert Irwin Hirsh, a seasoned biotech consultant concentrating on enhancing business efficiency and effectiveness, on how process mapping can transform your knowledge management and elevate your business performance.
Key Takeaways:
Tune in to uncover practical strategies that can transform your knowledge management practices and drive your biotech endeavors to new heights.
Connect with Irwin Hirsh:
LinkedIn: https://www.linkedin.com/in/ishirsh
Q-Specialists AB: https://www.qspecialists.com
Next Steps:
Wondering how to develop biologics and cell & gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at https://bruehlmann-consulting.com
Get ready to dive into the fascinating world of cryopreservation!
In this episode, we welcome Mark Davison, an experienced entrepreneur and CEO of Grant Instruments, leaders in laboratory equipment, to explore the intricate science of freezing and thawing cells.
Mark brings his wealth of experience to demystify this crucial process, revealing how cutting-edge technology ensures precision and reliability in preserving biological samples.
Key Takeaways:
Tune in for an insightful conversation that blends technical expertise with practical advice, perfect for scientists and entrepreneurs alike!
Connect with Mark Davison:
LinkedIn: https://www.linkedin.com/in/markdavison100
The Big Experiment podcast: https://thebigexperiment.buzzsprout.com
Grant Instruments: https://www.grantinstruments.com
Next Steps:
Wondering how to develop biologics and cell & gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at https://bruehlmann-consulting.com
Picture a world where we can freeze cells and bring them back to life perfectly intact.
In this episode, we're joined by Mark Davison, a leading expert in cryopreservation and CEO of Grant Instruments to uncover the intricate science of freezing and thawing cells. From basic principles to advanced techniques, we delve into how cryopreservation is revolutionizing biotechnology and cell therapies.
Key Takeaways:
Tune in to explore how cryopreservation is shaping the future of biotech!
Connect with Mark Davison:
LinkedIn: https://www.linkedin.com/in/markdavison100
The Big Experiment podcast: https://thebigexperiment.buzzsprout.com
Grant Instruments: https://www.grantinstruments.com
Next Steps:
Wondering how to develop biologics and cell & gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at https://bruehlmann-consulting.com
Could sound waves be the revolutionary key to gene therapy manufacturing? In this episode, Gabriel Dumy, CTO and Co-founder at Kolibri, reveals how acoustic waves are set to transform cell harvesting and gene transfection processes, making biomanufacturing more efficient and less damaging to cells.
Kolibri is a company revolutionizing the way we grow and engineer cells at scale using acoustic waves.
Key Takeaways:
Join us to explore how these advancements could revolutionize the future of gene therapy and beyond!
Connect with Gabriel Dumy
LinkedIn: https://www.linkedin.com/in/gabrieldumy
Kolibri: https://www.kolibrilab.com
Next Steps:
Wondering how to develop biologics and cell & gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at https://bruehlmann-consulting.com
Are sound waves the key to revolutionizing gene therapy? In this groundbreaking episode, we sit down with Gabriel Dumy, CTO and Co-founder at Kolibri, a company revolutionizing the way we grow and engineer cells at scale using acoustic waves.
Gabriel shares the challenges facing modern bioproduction and unveils an exciting solution that's setting the stage for the future of gene therapy.
Key Takeaways:
Tune in to find out how acoustic waves could be the breakthrough gene therapy has been waiting for!
Connect with Gabriel Dumy
LinkedIn: https://www.linkedin.com/in/gabrieldumy
Kolibri: https://www.kolibrilab.com
Next Steps:
Wondering how to develop biologics and cell & gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Develop biologics better, faster, at a fraction of the cost with our Fractional CTO services. Curious? DM us at https://bruehlmann-consulting.com
Dive into the future of bioprocessing with Nils Brechmann, Marketing Manager at MAGic BioProcessing and co-inventor of the process applications, as we explore how magnetic bead technology is transforming downstream processing.
MAGic BioProcessing is a biotech company from Uppsala, Sweden, that develops magnetic-based recovery of biologicals.
Key Takeaways:
Join us for an in-depth look at the benefits and innovations of magnetic bead technology in modern bioprocessing.
Connect with Nils Brechmann:
LinkedIn: https://www.linkedin.com/in/nils-brechmann-ph-d-44205114a
MAGic BioProcessing: https://magicbioprocessing.com
Next Step:
Enhance your bioprocess development strategy! Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Dive into the latest episode as we explore how magnetic bead technology is revolutionizing downstream processing, promising higher yields and greater purity.
Our guest, Nils Brechmann, Marketing Manager at MAGic BioProcessing and co-inventor of the process applications, shares his insights on overcoming industry challenges and the future of purification. MAGic BioProcessing is a biotech company from Uppsala, Sweden, that develops magnetic-based recovery of biologicals.
Key Takeaways:
Ready to elevate your bioprocessing game? Tune in now and harness the power of magnetic bead technology.
Connect with Nils Brechmann:
LinkedIn: https://www.linkedin.com/in/nils-brechmann-ph-d-44205114a
MAGic BioProcessing: https://magicbioprocessing.com
Next Step:
Enhance your bioprocess development strategy! Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Unlock the future of epigenetics and join us for an insightful conversation with Jonathon Hill as he delves into the groundbreaking world of next-generation sequencing (NGS) and its transformative impact on science and medicine. Jonathon Hill is the VP of Science and Technology and a co-founder of Wasatch BioLabs and Associate Professor of Cell Biology and Physiology at Brigham Young University.
Discover how cutting-edge nanopore technology is overcoming the limitations of traditional methods and revolutionizing epigenetic research.
Key Takeaways:
Don't miss this episode packed with innovative insights and the future landscape of genomic technology.
Connect with Jonathon Hill:
LinkedIn: https://www.linkedin.com/in/jonathon-t-hill
Wasatch BioLabs: https://www.wasatchbiolabs.com
Next Steps:
Schedule your free assessment to take process development to the next level now at https://bruehlmann-consulting.com/assessment
Curious about the latest advancements in next-generation sequencing (NGS) and how they are revolutionizing science and medicine?
In this episode, we delve into the cutting-edge developments of NGS with our expert guest, Jonathon Hill, VP of Science and Technology and a co-founder of Wasatch BioLabs and Associate Professor of Cell Biology and Physiology at Brigham Young University, who has been at the forefront of this transformative field.
Key Takeaways:
Join us to get an insider's view on how NGS is not only changing the landscape of research but also making a profound impact on human health. Don't miss this informative conversation with a leading expert in the field!
Connect with Jonathon Hill:
LinkedIn: https://www.linkedin.com/in/jonathon-t-hill
Wasatch BioLabs: https://www.wasatchbiolabs.com
Next Steps:
Schedule your free assessment to take process development to the next level now at https://bruehlmann-consulting.com/assessment
Dive into the realm of biotech with our latest episode as we unravel the enigma of Quality by Design (QbD) with Matthias Müllner, CEO of & Co-Founder bespark*bio, a company empowering viral vector-based medicines.
Discover how integrating QbD principles early in your development cycle can revolutionize your approach to producing safe, high-quality products consistently. From understanding critical quality attributes to designing robust manufacturing processes, we illuminate the transformative potential of QbD.
Key Takeaways:
Tune in to learn how a solid CMC strategy can be the cornerstone of your biotech product's success and ensure you avoid common mistakes that could derail your project.
Connect with Matthias Müllner:
LinkedIn: https://www.linkedin.com/in/matthias-muellner
Next Step:
Enhance your bioprocess development strategy! Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Join us for an insightful episode as we dive into the world of bioprocess CMC development strategies with Matthias Müllner, CEO of & Co-Founder bespark*bio, a company empowering viral vector-based medicines.
Matthias shares his wealth of knowledge on avoiding common pitfalls in developing robust Chemistry, Manufacturing, and Controls (CMC) strategies. He also emphasizes the critical elements that ensure your biotech product's success.
Key Takeaways:
Tune in to learn how a solid CMC strategy can be the cornerstone of your biotech product's success and ensure you avoid common mistakes that could derail your project.
Connect with Matthias Müllner:
LinkedIn: https://www.linkedin.com/in/matthias-muellner
Next Step:
Enhance your bioprocess development strategy! Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Is cultivated meat the food of tomorrow or just a passing trend? In this episode, we dive deep with Steven Lang, an expert in the field of cultivated meat. Steven sheds light on the intricate process of creating meat in the lab, the challenges faced, and the potential future of this innovative industry.
Key Takeaways:
Tune in to explore whether cultivated meat is the future we’ve been waiting for or just a bubble waiting to burst.
Connect with Steven Lang:
LinkedIn: https://www.linkedin.com/in/steven-lang-b003406
Next Step:
Don't miss out on boosting your bioprocess development strategy! Schedule your complimentary assessment to propel your success: https://bruehlmann-consulting.com/assessment
How can you create an environment suitable for shear-stress-sensitive cells that results in higher cell concentrations and superior quality? Essentially, bionic bioreactors revolutionize this process, changing the game rules with their ability to facilitate bubble-free gas exchange.
Join us in this episode as we unravel the groundbreaking innovations in bioreactor technology with our guest, Patrick Bongartz, CEO of BioThrust and the visionary mind behind stress-free cell cultivation.
Key Highlights:
Embark on a journey of scientific breakthroughs and entrepreneurial resilience in this episode.
Connect with Patrick Bongartz:
Website: https://biothrust.de
Linkedin BioThrust: https://www.linkedin.com/company/biothrust-de
Instagram: https://www.instagram.com/biothrust
Patrick’s LinkedIn: https://www.linkedin.com/in/patrick-bongartz-1106/
Next Step:
Wondering how to develop biologics and cell & gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
How can you create an environment suitable for shear-stress-sensitive cells that results in higher cell concentrations and superior quality? Essentially, bionic bioreactors revolutionize this process, changing the game rules with their ability to facilitate bubble-free gas exchange.
Join us in this episode as we unravel the groundbreaking innovations in bioreactor technology with our guest, Patrick Bongartz, CEO of BioThrust and the visionary mind behind stress-free cell cultivation.
Key Highlights:
Embark on a journey of scientific breakthroughs and entrepreneurial resilience in this episode.
Connect with Patrick Bongartz:
Website: https://biothrust.de
Linkedin BioThrust https://www.linkedin.com/company/biothrust-de
Instagram: https://www.instagram.com/biothrust
Patrick’s LinkedIn: https://www.linkedin.com/in/patrick-bongartz-1106/
Next Step:
Wondering how to develop biologics and cell & gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
How can you provide stress-free cultivation conditions to achieve higher cell concentrations and quality? In a nutshell, bionic bioreactors and thus change bubble-free gas exchange change the game.
Join us as we delve into the future of biotech with our guest, Patrick Bongartz, CEO of BioThrust and an expert in innovative bioreactor design.
Key Highlights:
Discover how bionic bioreactors are paving the way for a stress-free future in cell cultivation.
Connect with Patrick Bongartz:
Website: https://biothrust.de
Linkedin BioThrust https://www.linkedin.com/company/biothrust-de
Instagram: https://www.instagram.com/biothrust
Patrick’s LinkedIn: https://www.linkedin.com/in/patrick-bongartz-1106/
Next Step:
Wondering how to develop biologics and cell & gene therapies with peace of mind? Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Does the process of commercializing cell and gene therapies seem complex and unclear to you?
Dive deep into the groundbreaking world of cell and gene therapies with our guest, Wajiha Ali, a strategy expert who believes in bridging the gap between research and commercialization with data, as we unravel the complexities of bringing life-saving therapies to patients.
From cutting-edge technologies to innovative collaboration models, we explore the future landscape of these transformative treatments.
You’ll get:
Join us on this insightful journey into the future of cell and gene therapies.
Connect with Wajiha Ali:
LinkedIn: https://www.linkedin.com/in/wajiha-ali-6468454
X (Twitter): https://twitter.com/Wajihaali
Next Step:
Develop biologics and cell & gene therapies with peace of mind. Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Are you finding the path to commercializing cell and gene therapies complex and uncertain?
Join us as we explore this intricate landscape with our guest, Wajiha Ali. As a strategy expert who believes in bridging the gap between research and commericalization with data who she will guide us through the challenges, victories, and vital strategies for successfully bringing these cutting-edge therapies to market.
Key Highlights:
Tune in as we navigate the journey from scientific breakthroughs to real-world application, unraveling the complexities shaping the future of healthcare.
Connect with Wajiha Ali:
LinkedIn: https://www.linkedin.com/in/wajiha-ali-6468454
X (Twitter): https://twitter.com/Wajihaali
Next Step:
Develop biologics and cell & gene therapies with peace of mind. Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
In the second part of "Decode Bioprocess Success: The Art of Stakeholder Management," we delve deeper into the strategies for effective stakeholder management in bioprocess development.
Through a step-by-step approach, we explore how to identify, classify, and engage with stakeholders to ensure project success.
Key highlights:
Join us as we uncover the art of stakeholder management and its transformative impact on bioprocess development success. Don't miss out on this episode filled with practical advice and actionable strategies for mastering stakeholder engagement in bioprocess projects.
Next Step:
Boost your bioprocess strategy! Book your free assessment for success: https://bruehlmann-consulting.com/assessment
In this episode, we embark on a journey to uncover the essential strategies for navigating stakeholder relationships in bioprocess CMC development projects.
We delve into the critical role of stakeholders in bioprocess development and how their engagement can determine the success or failure of a project. Drawing from real-life experiences and insights, we explore the importance of understanding stakeholder needs, interests, and power dynamics.
Discover why stakeholder management is not just a skill but an art form essential for unlocking bioprocess success. Join us as we unravel the complexities of stakeholder engagement and provide actionable tips for mastering this crucial aspect of bioprocess development.
Tune in to learn how decoding the dynamics of stakeholder management can lead to triumph in bioprocess projects.
Next Step:
Boost your bioprocess strategy! Book your free assessment for success: https://bruehlmann-consulting.com/assessment
Unlock the secrets to cost-efficient antibody therapeutics with Brian Kelley, Senior Vice President of Process Development at VIR Biotechnology.
In this illuminating episode, industry expert Brian Kelley shares invaluable insights into driving down manufacturing costs while maintaining quality and accessibility. From optimizing batch sizes to maximizing titers, discover practical strategies to streamline the process economics of antibody development.
Key Takeaways:
Join us as we unravel the future landscape of antibody production, where simplicity and innovation converge to shape the next frontier of healthcare solutions. Tune in now for actionable strategies and visionary perspectives on mastering process economics in antibody therapeutics.
Connect with Brian Kelley:
LinkedIn: https://www.linkedin.com/in/brian-kelley-3389375
Next Step:
Enhance your bioprocess development strategy! Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Join us in this enlightening episode as we explore process economics with industry expert Brian Kelley. He is the Senior Vice President of Process Development at VIR Biotechnology.
Unraveling the mysteries of cost management in antibody therapeutics, Brian sheds light on the intricate challenges faced by biotech scientists and engineers.
Key Highlights:
Tune in for a masterclass in maximizing efficiency and driving down costs in the dynamic landscape of biologics production.
Connect with Brian Kelley:
LinkedIn: https://www.linkedin.com/in/brian-kelley-3389375
Next Step:
Enhance your bioprocess development strategy! Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Dive into the future of food with our latest episode, "From Lab to Table: The Science Behind Cultivated Meat." With our guest, Petra Hanga, a Lecturer in Biochemical Engineering at University College London and Chief Scientific Officer of Quest Meat Ltd., we unravel the secrets behind this groundbreaking technology.
Key highlights:
1. Discover how stem cells revolutionize the production of cultivated meat, providing a scalable solution for creating muscle, fat, and connective tissues.
2. Explore the intricate balance of nutrients, growth factors, and environmental conditions crucial for maximizing cell growth and quality.
3. Understand the challenges and breakthroughs in scaling up bioreactor processes for efficient meat production.
Join us for an informative discussion on the cutting edge of food technology. Gain valuable insights into the process of transforming lab-grown cells into delectable dishes on your table.
Don't miss out on this compelling episode!
Connect with Petra Hanga:
LinkedIn: https://www.linkedin.com/in/petrahanga/
Twitter: @PetraHanga
Next Step:
Enhance your bioprocess development strategy! Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Dive into the fascinating world of cultivated meat with our guest, Petra Hanga, Lecturer in Biochemical Engineering – Cellular Agriculture at University College London and the Chief Scientific Officer of Quest Meat Ltd.
In this episode, Petra sheds light on the intricacies of developing cultivated meat and reveals the key hurdles biotech scientists face.
Highlights:
Join us as we explore the promising landscape of cultivated meat, where science and innovation converge to shape a more sustainable future.
Enjoy your listening!
Connect with Petra Hanga:
LinkedIn: https://www.linkedin.com/in/petrahanga/
Twitter: @PetraHanga
Next Step:
Enhance your bioprocess development strategy! Schedule your free assessment to propel your success: https://bruehlmann-consulting.com/assessment
Does uncovering the secrets of glycan engineering feel like navigating a maze of molecular complexity?
In this captivating continuation of our exploration into the world of glycan engineering, we delve deeper into groundbreaking innovations and the crucial role of analytics in ensuring consistent quality.
Henning von Horsten, Professor of Industrial Bioengineering at HTW Berlin (University of Applied Sciences in Berlin), shares the fascinating story behind a groundbreaking technology designed to modulate antibody-dependent cell-mediated cytotoxicity (ADCC).
You’ll get:
Connect with Henning von Horsten:
Next Step:
Elevate your bioprocess development strategy — Schedule your free assessment now: https://bruehlmann-consulting.com/assessment
Does unlocking the secrets of glycan engineering seem like navigating a labyrinth of molecular complexity?
In this episode, we delve into the pivotal role of glycans as critical quality attributes (CQAs) in biotherapeutics.
Henning von Horsten, Professor of Industrial Bioengineering at HTW Berlin (University of Applied Sciences in Berlin), sheds light on the art and science of glycan engineering and analysis.
Key highlights:
Connect with Henning von Horsten:
Next Step:
Elevate your bioprocess development strategy — Schedule your free assessment now: https://bruehlmann-consulting.com/assessment
Hey, fellow scientists! Do you find yourself buried under an avalanche of tasks, unsure which one truly matters? If you're tired of the chaos and want to reclaim control of your time and energy, stick around.
Today, we're unlocking the secrets of Essentialism, tailor-made for busy biotech scientists like you. We discuss the importance of focusing on the vital few tasks that contribute significantly to your goals, celebrating small wins, and protecting your time.
We also share a powerful story that illustrates the potential of Essentialism. Discover how Essentialism is not about doing more, but doing the right things, and how this disciplined approach can lead you to significant breakthroughs in your bioprocess CMC development activities. This episode is a must-listen for any scientist and engineer who feels overcommitted, overloaded, or overworked.
Tune in to learn how to navigate the complex world of biotech process development in a more strategic, efficient, and successful way.
Next Step:
Elevate your bioprocess development strategy — Schedule your free assessment now: https://bruehlmann-consulting.com
Hey, fellow scientists! Do you find yourself buried under an avalanche of tasks, unsure which one truly matters? If you're tired of the chaos and want to reclaim control of your time and energy, stick around.
Today, we're unlocking the secrets of Essentialism, tailor-made for busy biotech scientists like you. We discuss the importance of focusing on the vital few tasks that contribute significantly to your goals, celebrating small wins, and protecting your time.
We also share a powerful story that illustrates the potential of Essentialism. Discover how Essentialism is not about doing more, but doing the right things, and how this disciplined approach can lead you to significant breakthroughs in your bioprocess CMC development activities. This episode is a must-listen for any scientist and engineer who feels overcommitted, overloaded, or overworked.
Tune in to learn how to navigate the complex world of biotech process development in a more strategic, efficient, and successful way.
Next Step:
Elevate your bioprocess development strategy — Schedule your free assessment now: https://bruehlmann-consulting.com
Explore the intricate world of perfusion and its sustainability challenges in the part 2 of this episode. Dive into the operational side of managing vast quantities of media production and storage, and discover smart strategies to address these challenges.
Jochen Sieck, Director of Cell Culture Media and Process Development at Merck Life Science, discusses the distinction between facility designs for batch and perfusion bioreactors, shedding light on the need for extensive tank farms to support perfusion.
Key Insights:
Tune in to discover how perfusion processes are revolutionizing the biotech industry and contributing to a more sustainable future.
Connect with Jochen Sieck:
LinkedIn: https://www.linkedin.com/in/jochenbsieck
ACTIP Fellowship award: https://www.actip.org/fellowship
Resources:
Perfusion Cell Culture Processes for Biopharmaceuticals by Moritz Wolf, Jean-Marc Bielser, and Massimo Morbidelli: https://www.cambridge.org/core/books/perfusion-cell-culture-processes-for-biopharmaceuticals/5C650AD26D52B2435E7796D382ECE5DA
Next Step:
Elevate your biologics development strategy — Schedule your free assessment now: https://bruehlmann-consulting.com
Explore perfusion processes and sustainability with our guest, Jochen Sieck, Director of Cell Culture Media and Process Development at Merck Life Science.
Learn about the evolution of perfusion methodologies, its historical roots in addressing product stability, and its recent return to continuous and integrated manufacturing.
Jochen discusses the economic and strategic reasons behind perfusion's resurgence, emphasizing the need for flexible, smaller-scale facilities.
Key Learnings:
Get ready to expand your understanding of perfusion processes, sustainability, and the delicate dance between economics and environmental consciousness.
Connect with Jochen Sieck:
LinkedIn: https://www.linkedin.com/in/jochenbsieck
ACTIP Fellowship award: https://www.actip.org/fellowship
Resources:
Perfusion Cell Culture Processes for Biopharmaceuticals by Moritz Wolf, Jean-Marc Bielser, and Massimo Morbidelli: https://www.cambridge.org/core/books/perfusion-cell-culture-processes-for-biopharmaceuticals/5C650AD26D52B2435E7796D382ECE5DA
Next Step:
Elevate your biologics development strategy — Schedule your free assessment now: https://bruehlmann-consulting.com
In part 2 of this insightful episode, we embark on a journey into the intricate world of biotech purification processes. Our guest, Wei Zhang, DSP Group Head at A*STAR Bioprocessing Technology Institute, delves into three key modalities, shedding light on the challenges and advancements in virus, RNA, and traditional vaccine purification.
You will learn:
Tune in as we unravel the complexities of downstream processing and glean valuable insights to excel in the dynamic field of bioprocessing purification.
Connect with Wei Zhang:
LinkedIn: https://www.linkedin.com/in/wei-zhang-a6539845
Next Step:
Elevate your bioprocess development capabilities — Schedule your free assessment now: https://bruehlmann-consulting.com
In this episode, Wei Zhang, DSP Group Head at A*STAR Bioprocessing Technology Institute, delves into the complexities of purification. Wei’s team pioneers bioprocessing processes for diverse biotherapeutics.
You will gain valuable insights into the intricate challenges and innovative solutions in bioprocessing purification.
You will learn:
The conversation unravels the evolving landscape of bioprocessing, where the emergence of complex drug modalities necessitates continuous advancements in purification techniques and tools.
Connect with Wei Zhang:
LinkedIn: https://www.linkedin.com/in/wei-zhang-a6539845
Next Step:
Elevate your bioprocess development capabilities — Schedule your free assessment now: https://bruehlmann-consulting.com
Welcome back to the second part of our insightful interview with Joel Eichmann, Managing Director of Green Elephant Biotech.
In this episode, we delve deeper into the technical aspects of adherent cell expansion systems, explore sustainable biotech practices, and discuss key considerations for cost-efficient and environmentally friendly bioprocessing.
Key Insights:
Whether you're a seasoned professional or a curious enthusiast, this episode provides a wealth of knowledge for those passionate about advancing biotech process develoment.
Contact Joel Eichmann:
LinkedIn: https://www.linkedin.com/in/joel-eichmann
Website: https://www.greenelephantbiotech.com
Next Step:
Elevate your biologics development strategy — Schedule your free assessment now: https://bruehlmann-consulting.com
Get ready for a deep dive into the world of bioprocess development as Joel Eichmann, Managing Director of Green Elephant Biotech, shares his expertise on smart strategies for adherent cell culture .
Join us as we unravel the intricacies of adherent cell culture and discover the innovative strategies shaping the future of bioprocess development.
You’ll get:
Join us for an insightful conversation and invaluable insights for biotech professionals, researchers, and enthusiasts like you looking to navigate the complexities of adherent cell culture and bioprocess development.
Contact Joel Eichmann:
LinkedIn: https://www.linkedin.com/in/joel-eichmann
Website: https://www.greenelephantbiotech.com
Next Step:
Elevate your biologics development strategy — Schedule your free assessment now: https://bruehlmann-consulting.com
Uncover the secrets of successful innovators, including Steve Jobs, Elon Musk, and Thomas Edison, in this enlightening episode of our podcast. We dive deep into the habits that set these trailblazers apart and fuel their innovative spirit.
Key learnings include:
These insights provide a roadmap to developing your own innovative mindset and achieving success. Don't miss out on these valuable insights that could ignite your innovative spirit. Tune in now!
Next Step:
Elevate your biologics development strategy — Grab your free assessment now: https://bruehlmann-consulting.com
Uncover the secrets of successful innovators, including Steve Jobs, Elon Musk, and Thomas Edison, in this enlightening episode of our podcast. We dive deep into the habits that set these trailblazers apart and fuel their innovative spirit.
Key learnings include:
These insights provide a roadmap to developing your own innovative mindset and achieving success. Don't miss out on these valuable insights that could ignite your innovative spirit. Tune in now!
Next Step:
Elevate your biologics development strategy — Grab your free assessment now: https://bruehlmann-consulting.com
Discover the hurdles and breakthroughs in glycoengineering, including the high costs of activated sugars.
Thomas Rexer, CTO of eversyn, a spin-off of the Max Planck Institute Magdeburg, unveils eversyn's multi-step biocatalysis process, designed to significantly drive down costs and make in vitro glycoengineering more accessible on a large scale.
Key Insights:
Connect with Thomas Rexer:
LinkedIn: https://www.linkedin.com/in/thomas-rexer
Website: www.eversyn.de
Next Step:
Elevate your bioprocess development strategy — Grab your free assessment now: https://bruehlmann-consulting.com
Get ready for a crash course in glycoengineering as Thomas Rexer, CTO of eversyn, a spin-off of the Max Planck Institute Magdeburg, breaks down the significance of modifying glycans in biopharmaceuticals.
Explore the science behind glycoengineering and its potential to enhance the properties of therapeutic proteins.
Key Insights:
Don't miss this episode as Thomas unveils the trends that will shape the future of glycoengineering, offering actionable insights for scientists, entrepreneurs, and biotech enthusiasts alike.
Connect with Thomas Rexer:
LinkedIn: https://www.linkedin.com/in/thomas-rexer
Website: www.eversyn.de
Next Step:
Elevate your bioprocess development strategy — Grab your free assessment now: https://bruehlmann-consulting.com
In our insightful second part of the conversation, we broaden our perspective to delve into the various modalities within the biotech industry, highlighting the unique and shared aspects of process development and scale-up.
Neil Templeton, the Director of Upstream Process Development at Solid Biosciences, passionately articulates his commitment towards making gene therapy more accessible. He does this by outlining strategic solutions to reduce the costs of development and manufacturing.
You will gain:
To connect with Neil Templeton and learn more about his work, visit his LinkedIn profile.
LinkedIn: https://www.linkedin.com/in/neil-templeton
Next Step:
Elevate your bioprocess development strategy — Grab your free assessment now: https://bruehlmann-consulting.com
In this enlightening episode, we're joined by Neil Templeton, Director in Upstream Process Development at Solid Biosciences, who pulls back the curtain on the intricate world of bioprocess development and manufacturing.
Neil delves into the shifting paradigms of the industry, sharing his expert insights on overcoming the unique challenges that surface when transitioning from R&D to GMP production. This episode is packed full of invaluable knowledge that's crucial for anyone looking to succeed in this field.
Key points we discuss include:
Get connected with Neil Templeton:
LinkedIn: https://www.linkedin.com/in/neil-templeton
Next Step:
Elevate your bioprocess development strategy — Grab your free assessment now: https://bruehlmann-consulting.com
Tackling bioprocess development and scale-up can be complex. While the science might be challenging, project management within biotech doesn't have to be.
In this engaging episode, we'll guide you on how to streamline your CMC development, demystifying the complexities of project planning and execution.
Here's what you'll gain:
Don't allow complexity to impede your progress - join us for these insights and beyond!
Next Step:
Elevate your bioprocess development strategy — Grab your free assessment now: https://bruehlmann-consulting.com
Bioprocess development and scale-up are complex. Science may give you headaches, but biotech project management should not.
In this riveting episode, you'll learn how to simplify your CMC development, guiding you through the maze of project planning and execution.
Key Takeaways:
Don't let complexity hold you back - tune in for these insights and more!
Next Step:
Elevate your bioprocess development strategy — Grab your free assessment now: https://bruehlmann-consulting.com
In this riveting episode of the Smart Biotech Scientist podcast, we navigate the intricate labyrinth of biotech scale-ups. We distill the process down to 9 essential steps for a smooth transition from laboratory to large-scale production.
Key Insights:
Equip yourself with the knowledge to not just endure tech transfers, but to excel.
Transform the tumult of tech transfer into a harmonious symphony with our expert guidance!
Next Step:
Elevate your bioprocess development strategy — Grab your free assessment now: https://bruehlmann-consulting.com
In this enlightening episode of the Smart Biotech Scientist podcast, we delve into the complex world of biotech scale-ups. We break down the 9 crucial steps to ensure a seamless transition from lab to large-scale production.
Top 3 Takeaways:
You will be armed with the knowledge to not just survive tech transfers, but to thrive.
Turn the tech transfer chaos into a well-orchestrated symphony with our expert insights!
Next Step:
Elevate your bioprocess development strategy — Grab your free assessment now: https://bruehlmann-consulting.com
If you've ever wondered how to seamlessly transition from R&D to process development, this is your golden ticket. Uncover practical strategies and expert advice that can be your compass through the intricate landscape of mastering CMC development.
Uncover the challenges and tactics to seamlessly navigate this critical phase.
Connect with Gene Lee:
LinkedIn: www.linkedin.com/in/gene-w-lee-phd-0318b83
Website: www.altrubio.com
Next Step:
Elevate your bioprocess development strategy — Grab your free assessment now: https://bruehlmann-consulting.com
Embark on a journey into the intricate world of CMC development with our latest episode, unraveling the challenges that often baffle biotech scientists. The complexity of CMC development is a formidable hurdle, and in this insightful discussion, we delve into strategies to master this critical process.
Key Takeaways:
Your journey to mastering CMC development starts here.
Connect with Gene Lee:
LinkedIn: www.linkedin.com/in/gene-w-lee-phd-0318b83
Website: www.altrubio.com
Next Step:
Elevate your bioprocess development strategy — Grab your free assessment now: https://bruehlmann-consulting.com
Are you looking for advanced strategies to enhance the quality and efficiency of cell therapy manufacturing processes?
In this episode with Shin Kawamata, CEO of Cyto-Facto Inc., we dive into the transformative power of digitization in cell therapy manufacturing and explore strategies to enhance efficiency and reduce costs.
Actionable Takeaways:
Join us as we uncover the latest advancements, challenges, and Shin's vision for the future of the cell therapy industry.
Connect with Shin:
Get Cell and Gene Therapy Training:
Are the escalating costs and intricate technical hurdles of cell therapy development causing you stress?
Tune into this insightful podcast episode featuring Shin Kawamata, CEO of Cyto-Facto Inc. in Kobe, Japan, who shares his expertise and innovative solutions to these pressing issues in the cell therapy industry.
Discover how to streamline your manufacturing processes, reduce costs, and enhance product quality, transforming the way you approach cell therapy development.
Key Takeaways:
Join us as we uncover the latest advancements, challenges, and Shin's vision for the future of the cell therapy industry.
Connect with Shin:
Get Cell and Gene Therapy Training:
Welcome to Part 2 of our conversation with Bernardo Estupiñán Gaisbauer, Principal at Drug Biologics Consulting.
In this insightful episode, we dive into the complex world of taking a molecule from the lab to clinical trials. Our guest shares invaluable insights into outsourcing strategies for biotech companies.
Key Learnings:
Join us for a deep dive into the outsourcing landscape, unraveling the intricacies of selecting the right partner and ensuring a successful collaboration. Tune in and elevate your biotech game!
Connect with Bernardo Estupiñán Gaisbauer:
Website: www.drugbiologics.com/cdmoadvisor
Article: In Search Of The Unicorn: Do End-To-End C(x)DMOs Really Exist?: www.bioprocessonline.com/doc/in-search-of-the-unicorn-do-end-to-end-c-x-dmos-really-exist-0001
Website: www.drugbiologics.com/cdmoadvisor
Article: In Search Of The Unicorn: Do End-To-End C(x)DMOs Really Exist?: www.bioprocessonline.com/doc/in-search-of-the-unicorn-do-end-to-end-c-x-dmos-really-exist-0001
In part 2 of this interview with Ioscani, Assistant Professor at the School of Chemical & Bioprocess Engineering, University College Dublin, we delve into the art and science of accelerating process development through the strategic extraction of valuable insights from data.
Our guest, a seasoned expert in computational modeling, unfolds the intricate dance between quality by design principles and data-driven approaches.
Key takeaways from this insightful conversation include:
Join us as we explore the transformative power of computational models in the biopharma sector, unlocking new possibilities for process optimization and efficiency.
Contact Ioscani Jiménez del Val:
Twitter: @UcdCell
LinkedIn: https://www.linkedin.com/in/ioscanij
Join us as we unravel the complexities of computational methods in bioprocessing, featuring cutting-edge research on glycosylation and process development.
Ioscani Jiménez del Val, Assistant Professor at the School of Chemical & Bioprocess Engineering, University College Dublin, explores the intricacies of creating computational models, closing the loop, and optimizing with numerical methods.
Discover the two broad flavors of modeling – kinetic and metabolic models – and how they contribute to understanding cellular processes in bioreactors.
Key Learnings:
Experience the journey of innovation as we explore how the revolutionary process of extracting valuable insights from your data is transforming the field of bioprocessing. Tune in now for an enlightening conversation with our esteemed expert guest.
Contact Ioscani Jiménez del Val:
Twitter: @UcdCell
LinkedIn: https://www.linkedin.com/in/ioscanij
In part 2, we explore the details of cost reduction in cultivated meat manufacturing, with a focus on two important factors: media and simplified bioreactors.
Beat Thalmann, a passionate innovator and serial entrepreneur specializing in the development of animal-free cell culture systems, highlights the strategic importance of selecting the right cells and advocates for a streamlined process that incorporates plant-based structures. This approach offers a cost-effective entry point for supermarkets.
Key Learnings:
Don't miss this engaging conversation that unlocks the future of sustainable and innovative meat production.
Connect with Beat Thalmann:
LinkedIn: https://www.linkedin.com/in/beatthalmann
Website: www.scinora.com
Is bacon without pigs the future? In this episode, join us as Beat Thalmann, a passionate innovator and serial entrepreneur specializing in the development of animal-free cell culture systems, unveils the exciting possibilities.
Discover how he overcomes the challenges of production and envisions a future where cultivated steak competes on price. Beat Thalmann provides an insider's perspective on the complexities of cell lines and production processes, exploring the intersection of biopharmaceuticals and cultivated meat.
Explore the innovative techniques companies are adopting, from rethinking bioreactors to recycling media, in their quest to bring affordable and sustainable alternatives to our plates.
You will Learn:
Tune in now to explore the future of bacon, steaks, and more – all without the need for traditional farming. It's a fascinating journey into the world of cultivated meat technology.
Connect with Beat Thalmann:
LinkedIn: https://www.linkedin.com/in/beatthalmann
Website: www.scinora.com
Are you struggling to unlock the full potential of Process Analytical Technology (PAT) in biomanufacturing?
Look no further!
Join us for a game-changing conversation with Abhijeet Satwekar, an Innovation Manager at Merck Guidonia-Rome, Italy.
Discover how PAT can revolutionize your decision-making, accelerate development timelines, and propel your biotech company to new heights.
Key Learnings:
Get ready to harness the power of PAT and gain a competitive edge in the digital transformation of biomanufacturing.
Don't miss out on this opportunity to become a PAT expert and unlock endless possibilities for success!
Connect with Abhijeet Satwekar:
Wondering how you can leverage the immense potential of the rapidly evolving world of digital transformation in biomanufacturing?
Join us as we explore the frontiers of technology and innovation with Abhijeet Satwekar, Innovation Manager at Merck Healthcare.
Discover how cutting-edge digital technologies are revolutionizing bioprocesses, optimizing efficiency, and ensuring consistent product quality.
Key Learnings:
Tune in for a wealth of knowledge that transcends the boundaries of traditional and digital realms in the quest for groundbreaking biologics.
Connect with Abhijeet Satwekar:
Welcome back to the second part of our exclusive interview with Steve Oh, former Institute Professor at the Bioprocessing Technology Institute (BTI) at the Agency for Science and Technology (A*STAR) and now Scientific Advisor to several international companies.
In this episode, Steve dives deep into the challenges of manufacturing different cell types, sharing insights gained from his groundbreaking research. From preventing spontaneous differentiation to optimizing multi-stage processes, Steve unveils the complexities of mastering cell therapy development.
Key Takeaways:
Join us as Steve shares invaluable insights into the intricate world of cell therapy, offering a roadmap for developers and industry leaders alike. Don't miss this episode packed with expertise and practical advice.
Currently, Steve is an Scientific Advisor to several international companies involved in lentivirus & AAV manufacturing, cryopreservation solutions, biodegradable/edible microcarriers, novel gene delivery methods, cultured meat and stem cell manufacturing.
Connect with Steve Oh:
Dive into the world of cell therapy process development with Steve Oh, former Institute Professor at the Bioprocessing Technology Institute (BTI) at the Agency for Science and Technology (A*STAR) and now Scientific Advisor to several international companies, as he shares thought-provoking perspectives and predictions on technologies that will impact the biotech industry.
In this riveting conversation, Steve Oh unveils secrets to consistent bioproducts and forecasts the future of cell and gene therapy.
Gain a deeper understanding of the evolving landscape and the challenges and opportunities it presents.
Key Takeaways:
Join the conversation as Steve Oh unfolds the intricate world of cell therapy process development, offering a roadmap from lab exploration to patient impact.
Currently, Steve is an Scientific Advisor to several international companies involved in lentivirus & AAV manufacturing, cryopreservation solutions, biodegradable/edible microcarriers, novel gene delivery methods, cultured meat and stem cell manufacturing.
Connect with Steve Oh:
Unlock the secrets of cell-line development with Tanner Nevill, the SVP of Applications at Bruker Cellular Analysis and one of the primary inventors and developers of the Beacon Optofluidic Platform.
In this interview, Tanner delves into the transformative power of nanopens and microenvironments in cell-line development.
Key Takeaways:
Join us as Tanner Nevill navigates the dynamic intersection of technology and life sciences, offering a glimpse into the evolving landscape of cell-line development.
Connect with Tanner Nevill:
For more on Tanner's insights and the revolutionary Beacon Optofluidic Platform, connect with him on LinkedIn or search for "beacon, CLD or CLD beacon."
LinkedIn: www.linkedin.com/in/tannernevill
Website: https://brukercellularanalysis.com/products/workflows/cell-line-development
In this episode, Tanner Nevill, the SVP of Applications at Bruker Cellular Analysis and one of the primary inventors and developers of the Beacon Optofluidic Platform, shares insights into revolutionizing cell-line development through nanopens and microenvironments.
Key Takeaways:
Join us as we uncover the dynamic intersection of science and engineering, challenging the norms in cell-line development.
Connect with Tanner Nevill:
LinkedIn: www.linkedin.com/in/tannernevill
Website: https://brukercellularanalysis.com/products/workflows/cell-line-development
In the second part of our insightful interview with Payar Radfar, CEO of Smart MCs, we delve into the practical steps of developing adherence cell cultures for bioprocessing scalability.
Payar emphasizes the critical need for patience and a methodical approach, recounting how many clients rush into large-scale cultures prematurely. The key takeaways include:
1. Start Small, Stay Patient: Begin with small cultures and test various microcarriers. Patience is crucial; rushing can lead to ambiguous results and hinder long-term success.
2. Role of Modeling: Payar discusses the potential of AI modeling in scaling up processes. While AI can save time, he emphasizes the importance of a cautious, step-by-step approach.
3. Avoid Pitfalls: Highlighting the diverse nature of cell types, microcarriers, and bioreactors, Payar warns against assuming uniformity. Each component plays a crucial role, requiring careful consideration and gradual adjustments.
Join us as we explore future trends in bioprocessing, where Payar anticipates breakthroughs in media formulation and the use of novel technologies like microfluidics. Discover the broad applications beyond cellular therapies and cultivated meat, reaching into vaccine production and other cell-dependent fields.
Tune in now to gain invaluable insights into the dynamic world of adherence cell cultures and the promising future of bioprocessing innovation.
Connect with Payar Radfar:
Website: https://smartmcs.com.au/
LinkedIn: linkedin.com/company/smart-mcs
Twitter: twitter.com/SmartMCsPTYLTD
In this episode, we explore the world of adherent cell cultures with Payar Radfar, CEO of Smart MCs. Smart MCs specializes in customized biomaterials and microfluidic solutions. Payar shares his unique journey in the biotech industry, driven by his passion for improving people's health.
Key Takeaways:
1. Revolutionizing Bioprocessing: Payar discusses the challenges scientists face when transitioning from lab-scale to industrial-scale production. He emphasizes the importance of a multidisciplinary approach and envisions his company playing a crucial role in simplifying and enhancing bioprocessing technologies.
2. Cost Challenges in Cellular Therapies: Payar addresses the high costs associated with cellular therapies and explores the barriers to wider distribution. He highlights the role of competition and regulations in reducing costs and increasing accessibility to these therapies.
3. The Power of Microcarriers: The technical discussion focuses on microcarriers and their vital role in adherent cell cultures. Payar explains how these microscopic spheres enable efficient scaling up of cell production in bioreactors, offering a glimpse into the future of bioprocessing.
Are you curious about the transformative potential of microcarriers and the future of bioprocessing?
Join us in this insightful conversation with Payar Radfar as we uncover the secrets behind scaling up adherent cell cultures and their profound impact on the biotech industry.
Connect with Payar Radfar:
Website: https://smartmcs.com.au/
LinkedIn: linkedin.com/company/smart-mcs
Twitter: twitter.com/SmartMCsPTYLTD
In the second part of our conversation with Michael Sokolov, the co-founder and COO of DataHow, we dive into practical insights on leveraging hybrid modeling in bioprocessing.
You will discover:
1. Starting Small, Dreaming Big: Even in smaller companies, you can start with a minimal number of reactors and still leverage hybrid modeling effectively. Whether it's just a few shakers or a handful of bioreactors, you can begin the journey to process improvement.
2. The Power of Digital Twins: Michael sheds light on the concept of digital twins, which involves creating a real-time model of your bioprocess. It not only helps optimize the process but also enables feedback control, reducing manual operations and adapting to changes on the fly.
3. Regulatory Acceptance: While the pharmaceutical industry is known for its conservatism, regulators are becoming more receptive to innovative technologies like hybrid modeling. Health authorities are encouraging the use of promising tools in process development and are not imposing specific technologies. As more companies adopt these tools and gather data on their effectiveness, they are likely to play a more prominent role in regulatory filings.
Don't miss out on this insightful discussion with Michael Sokolov as he unravels the potential of hybrid modeling in bioprocessing. If you're looking to simplify and streamline your bioprocessing journey, this episode is a must-listen.
Connect with Michael Sokolov:
Website: www.datahow.ch
In this insightful conversation, we explore how to accelerate bioprocess development and enhance manufacturing using hybrid modeling. Our guest, Michael Sokolov, COO of DataHow (a spin-off company from ETH Zurich), shares valuable insights.
Discover the three major takeaways that could transform the bioprocessing industry:
1. Unlocking the Power of Hybrid Modeling: Michael Sokolov introduces the revolutionary concept of hybrid modeling, which combines mechanistic knowledge with machine learning to expedite bioprocess development.
2. Accelerating Process Development: Learn how hybrid modeling can speed up your bioprocessing efforts, potentially allowing you to reduce the number of experiments by 60-80%, saving valuable time and resources.
3. Data-Driven Decision Making: Gain insights into how this approach enables data-driven decision making in the unpredictable world of biotech. It provides a deep understanding and empowers scientists to make informed choices.
Don't miss this episode for a comprehensive guide to smarter and more efficient bioprocessing!
Connect with Michael Sokolov:
Website: www.datahow.ch
In today's episode, we continue our fascinating conversation with Leonardo Sibilio, CEO of Biotech Academy and CSO at BetaPro Consulting. We delve into the pivotal role of structured training in the dynamic biotech industry.
In this episode, you'll discover:
- Foundation of Success: Leonardo emphasizes the importance of a strong foundation in GMP and an understanding of biotech facility operations. Whether you're an aspiring employee or a seasoned professional, a solid knowledge base in these areas is the cornerstone of a successful career.
- Broaden Your Horizons: Biotech is a multifaceted industry. Leonardo advises listeners to be curious and embrace a wide range of skills. You'll thrive by gaining expertise in both upstream and downstream processes, as well as analytical methods. This adaptability is key to succeeding in today's rapidly evolving biotech landscape.
- Continuous Learning: In the ever-changing world of biotech, continuous learning is vital. Leonardo recommends staying updated with technical literature, online courses, and hands-on training. To excel, it's crucial to master the practical aspects of bioreactor assembly, autoclaving, and equipment operation.
Join Leonardo as he explores the exciting opportunities in biotech, and find out how to enhance your expertise.
If you're passionate about biotech and eager to take your career to new heights, this episode is a must-listen! Don't miss out on the valuable insights Leonardo shares on mastering biotech scale-up. Tune in now!
Connect with Leonardo Sibilio:
In this episode with Tom Fletcher, R&D Director, Process development, Fujifilm Irvine Scientific, we delve into the world of bioprocessing. Tom shares insights into the transformative power of rational media design.
From the complexities of bioprocess development to the game-changing potential of AI, this interview is a treasure trove of knowledge for both scientists and engineers.
You will learn:
- Learn about the evolution of priorities during bioprocess development, from speed to reliability, and how scientists must adapt accordingly.
- Discover the importance of a thoughtful, hypothesis-driven approach compared to a blind, random one, and how it can reveal valuable process knowledge.
- Explore the exciting future of bioprocessing, including the role of AI and in silico models, and the importance of combining technology with human reasoning.
Tune in to gain a deeper understanding of the critical role that rational media design plays in advancing the biotech industry.
Connect with Tom Fletcher:
LinkedIn: https://www.linkedin.com/in/tomfletcher2
Fujifilm Irvine Scientific: https://www.irvinesci.com
Welcome to a fascinating Smart Biotech Scientist episode! In this conversation, we dive deep into the nuts and bolts of rational media development with our guest, Tom Fletcher, R&D Director, Process development, Fujifilm Irvine Scientific.
Together, we explore the immense potential of Rational Media Design and how it's transforming the industry.
Here are three major takeaways from this episode:
1. Define Your Goals: Tom emphasizes the importance of clearly defining your bioprocessing goals. Whether it's boosting cell growth or enhancing product quality, understanding your specific needs is the first crucial step.
2. Gain Process Understanding: Learn how to identify limiting factors in your process and generate hypotheses. Tom discusses how thinking through biochemical pathways and potential bottlenecks is key to achieving your goals.
3. Leverage Automation: Discover the future of bioprocessing with automated, closed systems that eliminate human intervention and ensure consistent, sterile media preparation. Tom shares insights into groundbreaking innovations that simplify and streamline the process.
Join us in unraveling the science behind bioprocessing and unlock the power of rational media design in this episode.
Don't miss out on the knowledge that could revolutionize your bioprocessing journey!
Connect with Tom Fletcher:
LinkedIn: https://www.linkedin.com/in/tomfletcher2
Fujifilm Irvine Scientific: https://www.irvinesci.com
In this captivating episode, we delve into the world of biotech scale-up with the seasoned expert, Leonardo Sibilio, CSO at BetaPro Consulting and CEO of the Biotech Academy in Rome.
Discover how mastering the art of biotech scale-up can transform your journey from doubt to dominance.
Key Takeaways:
1. Early Planning is Paramount: Leonardo emphasizes the importance of initiating the scale-up process as early as possible. Waiting until later phases can lead to challenges and hinder progress. Early planning, including characterizing the cell line and ensuring stability, is key to a seamless transition from R&D to large-scale production.
2. Mindset Shift is Crucial: Successful scale-up requires a shift in mindset, especially for startups originating from academia. Transitioning from research to regulated environments demands precision, rigorous documentation, and an unwavering focus on producing life-changing medicines.
3. Embrace Learning and Structured Processes: Leonardo encourages the use of structured methodologies and tools like R or Python for better data analysis and visualization. Structured documentation and reporting are critical for regulatory compliance and efficient tech transfer.
Join us as we explore the challenges, pitfalls, and strategies of biotech scale-up, unlocking the secrets to mastering it without guesswork.
Whether you're a seasoned professional or new to the field, this episode provides valuable insights for anyone interested in bioprocess scale-up and commercialization.
Connect with Leonardo Sibilio:
Are you a busy biotech scientist, trying to navigate the complex world of bioprocessing while fueling your passion for science? Join us on the Smart Biotech Scientist Podcast, where we're about to unravel the secrets to bioprocess mastery.
Hosted by a seasoned biotech leader and entrepreneur with over 15 years in the industry, this podcast is your compass through the maze of challenges. Picture yourself in the lab, deadlines looming, feeling like you're solving a puzzle with missing pieces. We've been there, too.
In this podcast, we simplify the journey to bioprocess mastery, providing practical solutions, deep dives into analytics, and inspiring conversations with biotech leaders. Imagine gaining insights from industry experts and belonging to a supportive community that fuels your growth.
Get ready for stories that resonate, solutions that empower, and questions that pique your curiosity. Don’t miss out!
►► Subscribe now, with new episodes dropping every Tuesday and Thursday.
Reignite your passion for science as we tackle challenges and simplify bioprocessing together. Join us on this exciting adventure!
En liten tjänst av I'm With Friends. Finns även på engelska.